Two Cases of Autoimmune Hemolytic Anemia Secondary to Brucellosis: A Review of Hemolytic Disorders in Patients with Brucellosis

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dc.contributor.authorEskazan, Ahmet Emre
dc.contributor.authorDal, Mehmet Sinan
dc.contributor.authorKaya, Safak
dc.contributor.authorDal, Tuba
dc.contributor.authorAyyildiz, Orhan
dc.contributor.authorSoysal, Teoman
dc.date.accessioned2024-04-24T17:18:32Z
dc.date.available2024-04-24T17:18:32Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBrucellosis is a worldwide zoonotic disease associated with hemolytic complications, including thrombotic microangiopathy (TMA) and hemolytic anemia. Autoimmune hemolytic anemia (AIHA) is a rare clinical presentation of this disease. In this report, we describe the cases of two patients with brucellosis who presented with Coombs-positive AIHA. We also include a review of the literature on the hemolytic complications of brucellosis. Both patients were successfully treated with a combination of doxycycline and rifampicin in addition to steroids. In the medical literature, there are several cases of TMA associated with brucellosis, although only a few cases of Coombs test-positive AIHA have been reported. Antibiotic therapy is the mainstay of treatment, and the selection of antibiotics and duration of treatment do not differ between brucellosis patients with and without hemolysis. Although rare, the potential for brucellosis should always be kept in mind in patients who present with hemolysis, especially those living in areas where brucellosis is endemic.en_US
dc.identifier.doi10.2169/internalmedicine.53.0936
dc.identifier.endpage1158en_US
dc.identifier.issn0918-2918
dc.identifier.issn1349-7235
dc.identifier.issue11en_US
dc.identifier.pmid24881740
dc.identifier.scopus2-s2.0-84901815819
dc.identifier.scopusqualityQ3
dc.identifier.startpage1153en_US
dc.identifier.urihttps://doi.org/10.2169/internalmedicine.53.0936
dc.identifier.urihttps://hdl.handle.net/11468/18820
dc.identifier.volume53en_US
dc.identifier.wosWOS:000336916900010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherJapan Soc Internal Medicineen_US
dc.relation.ispartofInternal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBrucellosisen_US
dc.subjectHemolysisen_US
dc.subjectAnemiaen_US
dc.subjectThrombotic Thrombocytopenic Purpuraen_US
dc.subjectCoombsen_US
dc.subjectRituximaben_US
dc.titleTwo Cases of Autoimmune Hemolytic Anemia Secondary to Brucellosis: A Review of Hemolytic Disorders in Patients with Brucellosisen_US
dc.titleTwo Cases of Autoimmune Hemolytic Anemia Secondary to Brucellosis: A Review of Hemolytic Disorders in Patients with Brucellosis
dc.typeReview Articleen_US

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