The histopathological effects of Thiodan® on the liver and gut of mosquitofish, Gambusia affinis
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Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Marcel Dekker Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Thiodan (R) (33.7% endosulfan), a polychlorinated cyclodiene insecticide, was evaluated for its histopathological effects on mosquitofish, Gambusia affinis, by light microscopy. Fish were exposed to doses of 0.00 (control), 1.00, 2.50, and 5.00 mug/L on days 7, 14, 21, and 30. No histopathological effects were apparent at control group. The histopathological alterations were characterized as oedema, degeneration, accumulation of lymphocytes in the lamina propria, disintegration of villuses, pycnotic state of nuclei, and necrosis in gut; degeneration, hypertrophy, sinusoids enlargement, hemorrhage, pycnosis position of nuclei, vacuolization of cell cytoplasm, infiltration of mononuclear lymphocyte, and congestion in liver. These alterations were time- and dose-dependent.
Açıklama
Anahtar Kelimeler
Pesticides, Gambusia Affinis, Histopathology, Gut, Liver
Kaynak
Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastes
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
36
Sayı
1