Comparing the effects of nebivolol and dexpanthenol on wound healing: an experimental study

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dc.contributor.authorUlger, Burak V.
dc.contributor.authorKapan, Murat
dc.contributor.authorUslukaya, Omer
dc.contributor.authorBozdag, Zubeyir
dc.contributor.authorTurkoglu, Ahmet
dc.contributor.authorAlabalik, Ulas
dc.contributor.authorOnder, Akin
dc.date.accessioned2024-04-24T17:11:29Z
dc.date.available2024-04-24T17:11:29Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractWound healing is a dynamic, interactive process that is initiated in response to injury. A number of investigations and clinical studies have been performed to determine new approaches for the improvement ofwound healing. The aim of this studywas to compare the effects of dexpanthenol, a molecule that is widely used for improvingwound healing, and nebivolol, a molecule that increases nitric oxide release, on wound healing. A total of 30 rats were divided into three equal groups (n = 10). A linear 2 cm incision was made in the rats' skin. No treatment was administered in the first (control) group. Dexpanthenol cream was administered to the rats in the second group and 5% nebivolol cream was administered to the rats in the third group. The wound areas of all of the rats were measured on certain days. On the 21st day, all wounds were excised and histologically evaluated. The wound healing rates of the dexpanthenol and nebivolol groups were higher than those of the control group (P < 0.05). However, the wound healing rates of the dexpanthenol and nebivolol groups were not significantly different. Nebivolol and dexpanthenol have comparable effects on wound healing.en_US
dc.description.sponsorshipDepartment of Pathologyen_US
dc.description.sponsorshipThe authors thank the Department of Pathology for their support during this study. The authors declare that they have no conflicts of interest.en_US
dc.identifier.doi10.1111/iwj.12314
dc.identifier.endpage371en_US
dc.identifier.issn1742-4801
dc.identifier.issn1742-481X
dc.identifier.issue3en_US
dc.identifier.pmid25040679
dc.identifier.scopus2-s2.0-84904238292
dc.identifier.scopusqualityQ1
dc.identifier.startpage367en_US
dc.identifier.urihttps://doi.org/10.1111/iwj.12314
dc.identifier.urihttps://hdl.handle.net/11468/17549
dc.identifier.volume13en_US
dc.identifier.wosWOS:000379940300010
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Wound Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDexpanthenolen_US
dc.subjectNebivololen_US
dc.subjectWound Healingen_US
dc.titleComparing the effects of nebivolol and dexpanthenol on wound healing: an experimental studyen_US
dc.titleComparing the effects of nebivolol and dexpanthenol on wound healing: an experimental study
dc.typeArticleen_US

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