Accelerated corneal collagen cross-linking for progressive keratoconus

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dc.contributor.authorCinar, Yasin
dc.contributor.authorCingu, Abdullah Kursat
dc.contributor.authorTurkcu, Fatih Mehmet
dc.contributor.authorYuksel, Harun
dc.contributor.authorSahin, Alparslan
dc.contributor.authorYildirim, Adnan
dc.contributor.authorCaca, Ihsan
dc.date.accessioned2024-04-24T17:20:36Z
dc.date.available2024-04-24T17:20:36Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: To evaluate the efficacy of accelerated corneal cross-linking (CXL) procedure for progressive keratoconus. Materials and methods: Twenty-three eyes of 23 patients undergone accelerated CXL procedure were evaluated preoperatively and postoperatively at 1st, 3rd and 6th month for uncorrected distant visual acuity (UDVA), best corrected distant visual acuity (CDVA), spherical error, cylindrical error, spherical equivalent (SE), keratometric values and thinnest corneal thickness (TCT) values with corneal topography by Scheimpflug camera and endothelial cell density (ECD). Results: The mean UDVA was improved from 0.97 +/- 0.41 logarithm of minimal angle of resolution (logMAR) to 0.76 +/- 0.45 logMAR at the 6th month after CXL (p = 0.332). The mean CDVA was improved from 0.49 +/- 0.30 logMAR to 0.34 +/- 0.22 logMAR at the 6th month after CXL (p = 0.026). The mean sphere was decreased from -4.47 +/- 4.1 diopter (D) to -3.79 +/- 3.86 D and the mean cylinder was decreased from -5.60 +/- 2.2D to -4.55 +/- 1.98 D and the mean SE was decreased from -7.22 +/- 4.48 D to -6.36 +/- 4.34 D at the 6th month after CXL (p = 0.128, p = 0.002 and p = 0.045, respectively). Flat keratometry, steep keratometry, mean keratometry and maximum keratometry were significantly reduced at the 6th month after CXL (p = 0.025, p < 0.001, p = 0.004 and p = 0.03, respectively). TCT and ECD were not changed significantly the 6th month after CXL (p = 0.135 and p = 0.082, respectively). Conclusion: Accelerated CXL procedure was effective to stabilize progression of keratoconus with significant reduction in topographic keratometric values and significant increase in CDVA in 6 months.en_US
dc.identifier.doi10.3109/15569527.2013.816724
dc.identifier.endpage171en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue2en_US
dc.identifier.pmid23879803
dc.identifier.scopus2-s2.0-84901320215
dc.identifier.scopusqualityQ3
dc.identifier.startpage168en_US
dc.identifier.urihttps://doi.org/10.3109/15569527.2013.816724
dc.identifier.urihttps://hdl.handle.net/11468/19151
dc.identifier.volume33en_US
dc.identifier.wosWOS:000336731700017
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous and Ocular Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCorneal Ectasiaen_US
dc.subjectCross-Linkingen_US
dc.subjectKeratoconusen_US
dc.titleAccelerated corneal collagen cross-linking for progressive keratoconusen_US
dc.titleAccelerated corneal collagen cross-linking for progressive keratoconus
dc.typeArticleen_US

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