Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia

Basit Öğe Kaydı
dc.contributor.authorKararmaz, A
dc.contributor.authorKaya, S
dc.contributor.authorTurhanoglu, S
dc.contributor.authorOzyilmaz, MA
dc.date.accessioned2024-04-24T16:19:11Z
dc.date.available2024-04-24T16:19:11Z
dc.date.issued2003
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: The purpose of this prospective study was to determine the effects of high-dose propofol on the incidence of fasciculations and myalgia, and to evaluate changes in creatine kinase levels following the administration of succinylcholine in 90 women who underwent laparoscopy. Methods: Patients were randomly assigned to one of three groups. Induction of anesthesia was performed with thiopentone 5 mg kg(-1) in Group I (n = 30), propofol 2 mg kg(-1) in Group II (n = 30), and propofol 3.5 mg kg(-1) in Group III (n = 30). Then succinylcholine 1 mg kg(-1) was administered to the patients for intubation. Results: Fasciculation was absent in 20% of Group III patients, and no vigorous fasciculation occurred in this group. Furthermore, the severity of fasciculation in Group III was significantly lower than in the other two groups (P = 0.01). Seventy per cent of patients had no myalgia in Group III, 39.2% in Group II and 37% in Group I (P = 0.007). Severity of myalgia was also significantly lower in Group III compared with the other two groups (P = 0.011). Post-operative creatine kinase levels were significantly higher than their baseline values in Groups I and II (P < 0.0001). Conclusion: Administration of propofol 3.5 mg kg(-1) is effective in reducing fasciculations and myalgia after succinylcholine.en_US
dc.identifier.doi10.1034/j.1399-6576.2003.00052.x
dc.identifier.endpage184en_US
dc.identifier.issn0001-5172
dc.identifier.issn1399-6576
dc.identifier.issue2en_US
dc.identifier.pmid12631047
dc.identifier.scopus2-s2.0-0037299909
dc.identifier.scopusqualityQ2
dc.identifier.startpage180en_US
dc.identifier.urihttps://doi.org/10.1034/j.1399-6576.2003.00052.x
dc.identifier.urihttps://hdl.handle.net/11468/16427
dc.identifier.volume47en_US
dc.identifier.wosWOS:000181398200009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofActa Anaesthesiologica Scandinavica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnestheticsen_US
dc.subjectPropofolen_US
dc.subjectComplicationsen_US
dc.subjectFasciculationsen_US
dc.subjectMyalgiaen_US
dc.subjectNeuromuscular Relaxantsen_US
dc.subjectSuxamethoniumen_US
dc.titleEffects of high-dose propofol on succinylcholine-induced fasciculations and myalgiaen_US
dc.titleEffects of high-dose propofol on succinylcholine-induced fasciculations and myalgia
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu