Prevalence and predictive factors for development of splenic artery aneurysms in cirrhosis

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dc.contributor.authorKaya, Muhsin
dc.contributor.authorBaran, Sengul
dc.contributor.authorGuya, Cemil
dc.contributor.authorKaplan, Mehmet Ali
dc.date.accessioned2024-04-24T16:02:50Z
dc.date.available2024-04-24T16:02:50Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractSplenic artery aneurysm (SAA) rarely occurs in the general population. Its increased incidence has been reported in cirrhosis. The aim of this retrospective study was to identify prevalence and predictive factor development of SAA in patients with cirrhosis. All patients with cirrhosis who were treated in our clinics between 2010 and 2014 were included in the study. Demographic features and clinical and laboratory findings were reviewed. Four-phase computerized tomography (CT) was used for identifying SAA. Imaging was reviewed for the presence of SAA as well as hepatic artery, portal vein, splenic artery, splenic vein, liver parenchyma, and intraabdominal cavity were evaluated. A total of 171 patients (age 55 +/- 13.9, 109 men) were included in the study. There was SAA in 27 (15.7 %) patients. Mean diameter of aneurysm was 11.66 (range, 6.06-27.1) mm. Aneurysm was located in the distal part of splenic artery in 20 (74 %) patients and solitary in 24 (88.8 %), and asymptomatic in all patients. Patients with SAA had larger portal vein and splenic vein compared to patients without SAA (15.3 +/- 3.9 vs. 13.1 +/- 2.9 mm, p=0.001; and 12.5 +/- 4.4 vs. 9.6 +/- 2.7 mm, p < 0.001, respectively). We identified positive correlation between development of SAA and splenic vein diameter [hazard ratio (HR) =1.23; 95 % confidence interval (CI) 0.97-1.57; p = 0.009] and negative correlation between hepatic artery diameter and development of SAA HR = 0.46; 95 % CI 0.25-0.85; p = 0.002). SAA occurred in a significant proportion of patients with cirrhosis, and enlargement of the splenic vein seemed to be a predictive factor for the development of SAA.en_US
dc.identifier.doi10.1007/s12664-016-0670-z
dc.identifier.endpage206en_US
dc.identifier.issn0254-8860
dc.identifier.issn0975-0711
dc.identifier.issue3en_US
dc.identifier.pmid27256433
dc.identifier.scopus2-s2.0-84975894152
dc.identifier.scopusqualityQ2
dc.identifier.startpage201en_US
dc.identifier.urihttps://doi.org/10.1007/s12664-016-0670-z
dc.identifier.urihttps://hdl.handle.net/11468/14930
dc.identifier.volume35en_US
dc.identifier.wosWOS:000379223300008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofIndian Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCirrhosisen_US
dc.subjectSplenic Artery Aneurysmen_US
dc.subjectSplenic Systemen_US
dc.titlePrevalence and predictive factors for development of splenic artery aneurysms in cirrhosisen_US
dc.titlePrevalence and predictive factors for development of splenic artery aneurysms in cirrhosis
dc.typeArticleen_US

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