Does contrast-enhanced computed tomography raise awareness in the diagnosis of the invisible side of celiac disease in adults?

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dc.authorid0000-0003-4551-8439en_US
dc.authorid0000-0003-4781-9729en_US
dc.contributor.authorGöya, Cemil
dc.contributor.authorDündar, İlyas
dc.contributor.authorÖzgökçe, Mesut
dc.contributor.authorTürko, Ensar
dc.contributor.authorÖzkaçmaz, Sercan
dc.contributor.authorDurmaz, Fatma
dc.contributor.authorAlabalık, Ulaş
dc.contributor.authorHattapoğlu, Salih
dc.date.accessioned2023-03-21T10:58:37Z
dc.date.available2023-03-21T10:58:37Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.description.abstractPurpose This study aimed to evaluate the diagnosis and determine major and minor criteria of celiac disease (CD) with the malabsorption patterns (MABP) in the small intestine and colon on computed tomography (CT) and additional CT findings. Methods This retrospective study was conducted with 116 patients diagnosed with CD, 14 CD patients recovering with treatment, and 35 control patients with non-CD. All patients had CT examinations and histopathological diagnoses. The sensitivity, specificity, PPV, NPV, and accuracy values of each CT finding defined in the literature were statistically evaluated. According to the patient and control groups, the numerical values of the findings and the sensitivity and specificity values were measured according to this cut-off value. The distribution of CT findings according to pathological Marsh data was evaluated in CD patients. Results Sensitivity and specificity were found to be higher in small bowel MABP findings, mesenteric hypervascularity, and increased SMV/aorta diameter. There was a numerically significant difference in MDCT findings between the control and pathological Marsh groups. In the ROC analysis performed in terms of the total numerical values of each MDCT finding observed between the groups, it was found that there were more than 7 MDCT findings, 100% sensitivity, and 92% specificity. The presence of four major and three minor criteria or three major and four minor criteria were considered significant. Conclusions Being aware of CT findings below the iceberg that may suggest CD in abdominal CT examinations performed in patients with atypical clinical and malabsorption findings or other nonspecific findings may prevent diagnostic delay and unnecessary procedures.en_US
dc.identifier.citationGöya, C., Dündar, İ., Özgökçe, M., Türko, E., Özkaçmaz, S., Durmaz, F. ve diğerleri. (2022). Does contrast-enhanced computed tomography raise awareness in the diagnosis of the invisible side of celiac disease in adults? Abdominal Radiology, 47(5 (SI)), 1750-1761.en_US
dc.identifier.doi10.1007/s00261-022-03480-x
dc.identifier.endpage1761en_US
dc.identifier.issn2366-004X
dc.identifier.issn2366-0058
dc.identifier.issue5 (SI)en_US
dc.identifier.pmid35279730
dc.identifier.scopus2-s2.0-85126118123
dc.identifier.scopusqualityQ1
dc.identifier.startpage1750en_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s00261-022-03480-x
dc.identifier.urihttps://hdl.handle.net/11468/11468
dc.identifier.volume47en_US
dc.identifier.wosWOS:000767904100002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAlabalık, Ulaş
dc.institutionauthorHattapoğlu, Salih
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAbdominal Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCeliac diseaseen_US
dc.subjectEnteropathyen_US
dc.subjectSmall bowel diseaseen_US
dc.subjectComputed tomographyen_US
dc.subjectDiagnosisen_US
dc.subjectIcebergen_US
dc.titleDoes contrast-enhanced computed tomography raise awareness in the diagnosis of the invisible side of celiac disease in adults?en_US
dc.titleDoes contrast-enhanced computed tomography raise awareness in the diagnosis of the invisible side of celiac disease in adults?
dc.typeArticleen_US

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