Acute bacterial meningitis as a complication of otitis media and related mortality factors

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dc.contributor.authorGeyik, MF
dc.contributor.authorKokoglu, OF
dc.contributor.authorHosoglu, S
dc.contributor.authorAyaz, C
dc.date.accessioned2024-04-24T17:20:47Z
dc.date.available2024-04-24T17:20:47Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the characteristics of patients with acute bacterial meningitis (ABM) developed secondary to acute and chronic otitis media (OM). Between 1991 and 2001, among 269 adult patients with ABM, 56 who were secondary to OM were included in the study. We reviewed the charts of patients who were diagnosed as ABM following acute or chronic OM. Risk factors associated with mortality were determined by using a logistic regression model. The mean age of the patients, 38 male and 18 female, was 25.8 +/- 10.8 years (range 14-65). Forty-four of these cases (79%) have had chronic OM, of whom 19 (43% of the 44) have also had chronic mastoiditis and 12 (27% of the 44) acute OM. Twenty-three patients (41%) died, during either hospitalization or the follow-up period. Univariate analysis revealed comatose mental status on admission, inappropriate antibiotic treatment before admission, and elevated erythrocyte sedimentation rate (ESR) as significant risk factors for mortality. In multifactorial analysis, comatose mental status (OR=42.5, CI=6.4-280.1, p=0.001) and elevated ESR (OR=1.0, CI=1.01-1.07; p=0.005) remained as significant predictors for mortality. In conclusion, die primary sources of infection leading to the development of ABM should be investigated carefully to reduce the morbidity and mortality rates. It is hoped that this study will raise awareness among general practitioners and otolaryngologists concerning the role of ABM as one of the most important complications of OM.en_US
dc.identifier.doi10.3349/ymj.2002.43.5.573
dc.identifier.endpage578en_US
dc.identifier.issn0513-5796
dc.identifier.issn1976-2437
dc.identifier.issue5en_US
dc.identifier.pmid12402369
dc.identifier.scopus2-s2.0-0036805492
dc.identifier.scopusqualityQ1
dc.identifier.startpage573en_US
dc.identifier.urihttps://doi.org/10.3349/ymj.2002.43.5.573
dc.identifier.urihttps://hdl.handle.net/11468/19249
dc.identifier.volume43en_US
dc.identifier.wosWOS:000179025100003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherYonsei Univ Coll Medicineen_US
dc.relation.ispartofYonsei Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMeningitisen_US
dc.subjectOtitis Mediaen_US
dc.subjectMortalityen_US
dc.subjectComplicationen_US
dc.titleAcute bacterial meningitis as a complication of otitis media and related mortality factorsen_US
dc.titleAcute bacterial meningitis as a complication of otitis media and related mortality factors
dc.typeArticleen_US

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