Evaluation of false negativity of the Widal test among culture proven typhoid fever cases

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dc.contributor.authorHoşoğlu, Salih
dc.contributor.authorBoşnak, Vuslat
dc.contributor.authorAkalın, Şerife
dc.contributor.authorGeyik, Mehmet Faruk
dc.contributor.authorAyaz, Celal
dc.date.accessioned2024-04-24T17:58:16Z
dc.date.available2024-04-24T17:58:16Z
dc.date.issued2008
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları Anabilim Dalıen_US
dc.description.abstractBACKGROUND: The Widal test is the most common, specific and quick diagnostic method available in the world for diagnosis of typhoid fever; however, false negativity is one of the obstructive features of the test. The aim of this study was to evaluate the associated factors with Widal test negativity in an endemic area. METHODS: Widal test negativity was retrospectively analyzed among culture-proven typhoid fever cases. The potential features including age, gender, previous antibiotic usage, duration of symptoms, leucopoenia, hematocrit value, and erythrocyte sedimentation rate (ESR) were evaluated for association with Widal test negativity. RESULTS: A total of 166 culture-proven typhoid fever cases (93 or 56.0% males) were included in the study. The mean age +/- SD was 23.3 +/- 10.6 years. Mean time of interval between first symptom and test performance time was 10.6 +/- 7.8 days. The Widal test (STO and/or STH) was found positive in 75 cases (45.2%). The statistical analyses revealed that none of these variables were significant for false negativity of the Widal test. Age was found to be a possible factor for a false negative Widal test (p=0.06). CONCLUSION: Of existing compatible clinical findings, age should be considered in cases of Widal test negativity.en_US
dc.identifier.citationHoşoğlu, S., Boşnak, V., Akalın, Ş., Geyik, M. F. ve Ayaz, C. (2008). Evaluation of false negativity of the Widal test among culture proven typhoid fever cases. Evaluation of false negativity of the Widal test among culture proven typhoid fever cases, 2(6), 475-478.
dc.identifier.doi10.3855/jidc.165
dc.identifier.endpage478en_US
dc.identifier.issn1972-2680
dc.identifier.issue6en_US
dc.identifier.pmid19745527
dc.identifier.scopus2-s2.0-73349104130
dc.identifier.scopusqualityQ2
dc.identifier.startpage475en_US
dc.identifier.urihttps://doi.org/10.3855/jidc.165
dc.identifier.urihttps://hdl.handle.net/11468/23782
dc.identifier.volume2en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofJournal of infection in developing countries
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of false negativity of the Widal test among culture proven typhoid fever casesen_US
dc.titleEvaluation of false negativity of the Widal test among culture proven typhoid fever cases
dc.typeArticleen_US

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