What does the procalcitonin level tell us in patients with acute pancreatitis?

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dc.authorid0000-0002-0908-1949en_US
dc.authorid0000-0001-8321-4829en_US
dc.authorid0000-0002-2677-3971en_US
dc.contributor.authorEbik, Berat
dc.contributor.authorKaçmaz, Hüseyin
dc.contributor.authorTuncel, Elif Tuğba
dc.contributor.authorArpa, Medeni
dc.contributor.authorUçmak, Feyzullah
dc.contributor.authorKaya, Muhsin
dc.date.accessioned2023-10-20T06:13:42Z
dc.date.available2023-10-20T06:13:42Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractObjective: To determine the factors affecting the procalcitonin level, and its association with the severity of pancreatitis in patients with acute pancreatitis (AP). Study Design: Cross-sectional analytical study. Place and Duration of Study: Division of Gastroenterology, University of Health Sciences, Diyarbakır Gazi Yasargil Education and Research Hospital and Department of Gastroenterology, Dicle University School of Medicine, Diyarbakır, Turkey, between April 2017 and June 2021. Methodology: The study included 214 patients diagnosed with AP according to Atlanta criteria. By checking the PCT and CRP values of the patients in the first 12 hours, the relationship with these scales that predict the severity of pancreatitis was statistically examined. Results: Hundred and fifty-two patients (71.0%) had mild, while 62 patients (29.0%) had severe pancreatitis. According to the Atlanta criteria, the mean PCT level of patients with mild pancreatitis was 1.4±0.7 ng/mL, while the mean PCT level of patients with severe pancreatitis was 9.0±12.3 ng/mL (p<0.001). The diagnostic performance of PCT was better for predicting severe AP. For the 0.94 ng/mL cut-off, PCT had 86.9% sensitivity and 50.7% specificity. (AUC=0.731[95% CI: 0.669-0.811]; p<0.001; LR: 1.7). In patients with severe pancreatitis, the PCT level was 4.7±18.5 ng/mL in patients without concomitant infection and 15.8±8.1 ng/mL in patients with concomitant infection (p<0.001). Conclusion: High PCT value measured at the time of the first admission to the hospital may predict severe pancreatitis. In addition, a high PCT value at the time of admission to the hospital in patients with pancreatitis may indicate another concomitant infection.en_US
dc.identifier.citationEbik, B., Kaçmaz, H., Tuncel, E. T., Arpa, M., Uçmak, F. ve Kaya, M. (2022). What does the procalcitonin level tell us in patients with acute pancreatitis?. Journal of the College of Physicians and Surgeons Pakistan, 32(10), 1272-1277.en_US
dc.identifier.doi10.29271/jcpsp.2022.10.1272
dc.identifier.endpage1277en_US
dc.identifier.issn1022-386X
dc.identifier.issue10en_US
dc.identifier.pmid36205270
dc.identifier.scopus2-s2.0-85139277062
dc.identifier.scopusqualityQ2
dc.identifier.startpage1272en_US
dc.identifier.urihttps://jcpsp.pk/article-detail/pwhat-does-the-procalcitonin-level-tell-us-in-patients-with-acute-pancreatitisorp
dc.identifier.urihttps://hdl.handle.net/11468/12888
dc.identifier.volume32en_US
dc.identifier.wosWOS:000886033700008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUçmak, Feyzullah
dc.institutionauthorKaya, Muhsin
dc.language.isoenen_US
dc.publisherCollege of Physicians and Surgeons Pakistanen_US
dc.relation.ispartofJournal of the College of Physicians and Surgeons Pakistan
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute pancreatitisen_US
dc.subjectCoinfectionen_US
dc.subjectProcalcitoninen_US
dc.subjectSeverity of pancreatitisen_US
dc.titleWhat does the procalcitonin level tell us in patients with acute pancreatitis?en_US
dc.titleWhat does the procalcitonin level tell us in patients with acute pancreatitis?
dc.typeArticleen_US

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