Serum relaxin levels in benign hypermobility syndrome

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dc.contributor.authorEm, Serda
dc.contributor.authorOktayoglu, Pelin
dc.contributor.authorBozkurt, Mehtap
dc.contributor.authorCaglayan, Mehmet
dc.contributor.authorKarakoc, Mehmet
dc.contributor.authorUcar, Demet
dc.contributor.authorVerim, Sabahattin
dc.date.accessioned2024-04-24T17:20:40Z
dc.date.available2024-04-24T17:20:40Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: In this study, we investigated the activity of serum relaxin in female patients with benign joint hypermobility syndrome (BJHS), locomotor system findings accompanying BJHS, and its relation to relaxin. METHODS: Into the study, female patients with BJHS and healthy women as the control group were included. The patients were diagnosed by using the Brighton 1998 criteria. Examination of the locomotor system for study groups were performed. Serum relaxin levels of both patient and control group were measured. RESULTS: There were 48 female patients with BJHS and 40 healthy women in the study. With respect to the control group, the level of serum relaxin was higher in the patients (47.1 +/- 20.3, 34.4 +/- 22.1; p > 0.05). Again compared with the control group, arthralgia (p = 0.00), myalgia (p = 0.01), shoulder impingement syndrome (p = 0.05), pes planus (p = 0.01), and hyperkyphosis (p = 0.000) were higher in the patients. The level of relaxin median was significantly higher in the patients with pesplanus and hyperkyphosis than those who did not have them (p = 0.05, p = 0.01, respectively). CONCLUSIONS: Although serum relaxin level is not considered a causative factor for BJHS, the significant increases found in those patients with hyperkyphosis and pes planus suggest the hypothesis that relaxin has a limited and indefinite role in patients with BJHS.en_US
dc.identifier.doi10.3233/BMR-140543
dc.identifier.endpage479en_US
dc.identifier.issn1053-8127
dc.identifier.issn1878-6324
dc.identifier.issue3en_US
dc.identifier.pmid25322737
dc.identifier.scopus2-s2.0-84933054459
dc.identifier.scopusqualityQ2
dc.identifier.startpage473en_US
dc.identifier.urihttps://doi.org/10.3233/BMR-140543
dc.identifier.urihttps://hdl.handle.net/11468/19193
dc.identifier.volume28en_US
dc.identifier.wosWOS:000356810600007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherIos Pressen_US
dc.relation.ispartofJournal of Back and Musculoskeletal Rehabilitation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRelaxinen_US
dc.subjectJoint Hypermobility Syndromeen_US
dc.subjectCollagenen_US
dc.subjectLigamenten_US
dc.titleSerum relaxin levels in benign hypermobility syndromeen_US
dc.titleSerum relaxin levels in benign hypermobility syndrome
dc.typeArticleen_US

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