Easier and more explanatory indices by integrating leukocyte lymphocyte ratio (LLR) and prognostic nutritional index (PNI) to IPS systems in cases with classical Hodgkin lymphoma

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dc.contributor.authorPaydas, Semra
dc.contributor.authorLacin, Sahin
dc.contributor.authorDogan, Mutlu
dc.contributor.authorBarista, Ibrahim
dc.contributor.authorYildiz, Birol
dc.contributor.authorSeydaoglu, Gulsah
dc.contributor.authorKaradurmus, Nuri
dc.date.accessioned2024-04-24T16:15:25Z
dc.date.available2024-04-24T16:15:25Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study is to determine the power of he international prognostic scoring systems (IPS-7 and IPS-3) and to obtain indices by integrating leukocyte lymphocyte ratio (LLR) and prognostic nutritional index (PNI) factors as prognostic indicators in cases with classical Hodgkin lymphoma (cHL). 1012 patients with cHL were evaluated with 2 different IPS-4 scores with four parameters: stage, age, hemoglobin level, and either LLR or PNI. Statistical package SPSS v 22.0 was used. Two different Cox regression models were obtained for OS and PFS. Model 1 showed LLR >= 5,8 as the highest risk for OS and anemia as the highest risk for PFS. Model 2 showed PNI <= 45,2 as the highest risk for OS and anemia as the highest risk for PFS. IPS-4 scores obtained by integrating either LLR or PNI to IPS-3 integration of a biologic parameter either LLR or PNI need to be determined with clinical risk scoring parameters.en_US
dc.identifier.doi10.1016/j.leukres.2021.106586
dc.identifier.issn0145-2126
dc.identifier.issn1873-5835
dc.identifier.pmid34082249
dc.identifier.scopus2-s2.0-85107038960
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1016/j.leukres.2021.106586
dc.identifier.urihttps://hdl.handle.net/11468/15792
dc.identifier.volume107en_US
dc.identifier.wosWOS:000683559400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofLeukemia Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHodgkin Lymphomaen_US
dc.subjectIps-4en_US
dc.subjectPnien_US
dc.subjectLlren_US
dc.subjectInflammatory Indicesen_US
dc.titleEasier and more explanatory indices by integrating leukocyte lymphocyte ratio (LLR) and prognostic nutritional index (PNI) to IPS systems in cases with classical Hodgkin lymphomaen_US
dc.titleEasier and more explanatory indices by integrating leukocyte lymphocyte ratio (LLR) and prognostic nutritional index (PNI) to IPS systems in cases with classical Hodgkin lymphoma
dc.typeArticleen_US

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