Visceral Fat Reflects Disease Activity in Patients with Ankylosing Spondylitis

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dc.contributor.authorAydin, Mesut
dc.contributor.authorAydin, Fatma
dc.contributor.authorYuksel, Murat
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorPolat, Nihat
dc.contributor.authorAkil, Mehmet A.
dc.contributor.authorBilik, Mehmet Z.
dc.date.accessioned2024-04-24T17:40:01Z
dc.date.available2024-04-24T17:40:01Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: Response to infiiximab treatment diminishes as body mass index (BMI) increases in patients with ankylosing spondylitis (AS). The purpose of the study was to determine if diminished response to in fliximab treatment in patients with AS could be associated with increased visceral adipose tissue rather than increased BMI. Methods: Twenty six AS patients (21 males and five females) who fulfilled the modifid New York criteria and who were currently receiving infiiximab treatment were enrolled in the study. Pain was measured by the visual analogue scale (VAS). The disease activity and functional status were assessed by the Bath AS Disease Activity Index (BASDAI) and the Bath AS Functional Index (BASFI). The Bath AS Metrology Index (BASMI) was used to evaluate mobility restrictions. Weight and visceral body composition were measured without shoes in light indoor clothes using a bio-impedance meter. Results: There was a significant correlation between visceral adipose tissue amount and disease activity under infiiximab treatment. In correlation analysis, visceral fat showed significant correlations between BASDAI (r=0.545, p=0.004) and VAS (r=0.458, p=0.019). Total body fat also showed a significant correlation with BASDAI (r=0.463, p=0.017). Conclusion: A significant correlation was found between visceral adipose tissue amount and disease activity in patients with AS.en_US
dc.identifier.endpageE190en_US
dc.identifier.issn0147-958X
dc.identifier.issn1488-2353
dc.identifier.issue3en_US
dc.identifier.pmid24895992
dc.identifier.scopus2-s2.0-84902179289
dc.identifier.scopusqualityQ2
dc.identifier.startpageE186en_US
dc.identifier.urihttps://hdl.handle.net/11468/21529
dc.identifier.volume37en_US
dc.identifier.wosWOS:000345902600008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherCanadian Soc Clinical Investigationen_US
dc.relation.ispartofClinical and Investigative Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleVisceral Fat Reflects Disease Activity in Patients with Ankylosing Spondylitisen_US
dc.titleVisceral Fat Reflects Disease Activity in Patients with Ankylosing Spondylitis
dc.typeArticleen_US

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