Relationship between Nadir Hematocrit during Cardiopulmonary Bypass and Postoperative Hyperglycemia in Nondiabetic Patients

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dc.contributor.authorSevuk, Utkan
dc.contributor.authorCakil, Nevzat
dc.contributor.authorAltindag, Rojhat
dc.contributor.authorBaysal, Erkan
dc.contributor.authorAltintas, Bernas
dc.contributor.authorYaylak, Baris
dc.contributor.authorAdiyaman, Mehmet Sahin
dc.date.accessioned2024-04-24T17:18:04Z
dc.date.available2024-04-24T17:18:04Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Hyperglycemia is common after cardiac surgery in both diabetic and nondiabetic patients and is associated with increased morbidity and mortality. Association between nadir hematocrit levels on cardiopulmonary bypass (CPB) and postoperative hyperglycemia is not clear. This study was carried out to determine the relationship between nadir hematocrit during CPB and postoperative hyperglycemia in nondiabetic patients. Methods: Records of 200 nondiabetic patients undergoing coronary artery bypass grafting operation were retrospectively reviewed. In the first analysis, patients were divided into two subgroups according to the presence or absence of hyperglycemia. Further analysis was made after dividing the patients into 3 subgroups according to nadir hematocrit levels on CPB (less than 20%; 20% to 25%; greater than or equal to 25%). Results: Compared to patients without hyperglycemia, patients with postoperative hyperglycemia had significantly lower preoperative hematocrit levels (p = 0.004) and were associated with lower nadir hematocrit levels during CPB (p=0.002). Peak intensive care unit blood glucose levels and number of blood transfusions were significantly higher in patients with nadir hematocrit levels less than 20. (p<0.001 and p<0.001 respectively). Logistic regression analysis demonstrated that nadir hematocrit levels less than 20% (OR 2.9, p=0.009) and allogenic blood transfusion (OR 1.5, p=0.003) were independently associated with postoperative hyperglycemia. Conclusions: Nadir hematocrit levels on CPB less than 20% and allogenic blood transfusions were independently associated with postoperative hyperglycemia in nondiabetic patients. Patients with a nadir hematocrit levels less than 20 % during CPB should be closely monitored for hyperglycemia in the perioperative period.en_US
dc.identifier.doi10.1532/HSF98.2014437
dc.identifier.endpageE307en_US
dc.identifier.issn1098-3511
dc.identifier.issn1522-6662
dc.identifier.issue6en_US
dc.identifier.pmid25586280
dc.identifier.scopus2-s2.0-84921456594
dc.identifier.scopusqualityQ3
dc.identifier.startpageE302en_US
dc.identifier.urihttps://doi.org/10.1532/HSF98.2014437
dc.identifier.urihttps://hdl.handle.net/11468/18577
dc.identifier.volume17en_US
dc.identifier.wosWOS:000347915000007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherForum Multimedia Publishing, Llcen_US
dc.relation.ispartofHeart Surgery Forum
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleRelationship between Nadir Hematocrit during Cardiopulmonary Bypass and Postoperative Hyperglycemia in Nondiabetic Patientsen_US
dc.titleRelationship between Nadir Hematocrit during Cardiopulmonary Bypass and Postoperative Hyperglycemia in Nondiabetic Patients
dc.typeArticleen_US

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