Role of Superb Microvascular Imaging (SMI) vascularity index values and vascularity patterns in the differential diagnosis of malignant liver lesions

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dc.authorid0000-0002-5255-8618
dc.authorid0000-0002-3240-6991
dc.contributor.authorAslan, Halil Serdar
dc.contributor.authorArslan, Muhammet
dc.contributor.authorAlver, Kadir Han
dc.contributor.authorVurgun, Sercan
dc.contributor.authorDemirci, Mahmut
dc.contributor.authorTekinhatun, Muhammed
dc.date.accessioned2025-02-22T14:09:07Z
dc.date.available2025-02-22T14:09:07Z
dc.date.issued2024
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalıen_US
dc.description.abstractPurposeTo evaluate the Superb Microvascular Imaging (SMI) vascular patterns and vascularity index (VI) values of malignant focal liver lesions (FLLs), assess their role in differential diagnosis, and examine interobserver agreement.Materials and methodsA total of 107 patients (52 males, 55 females; mean age 62 +/- 12.8 years, range 25-87) referred to the interventional radiology clinic for FLL biopsy between April 2022 and April 2023 were analyzed. Two radiologists independently assessed the SMI vascular patterns and calculated VI values. Differences among three lesion groups - hepatocellular carcinoma (HCC, n = 16), non-HCC primary liver malignancies (n = 16), and metastases (n = 75) - were evaluated, and interobserver agreement was assessed.ResultsMost metastases (88%) demonstrated hypovascular patterns, while HCCs predominantly exhibited hypervascular patterns (68.7-81.3%). Non-HCC primary malignancies showed no dominant vascular pattern. Significant differences in SMI patterns were observed among lesion types (p = 0.001-0.035). VI values for HCCs (7.53-7.73) were significantly higher than those for non-HCC malignancies (2.73-2.93) and metastases (1.35-1.36) (p = 0.0001). ROC analysis based on VI values yielded AUCs of 0.886-0.887, with a cutoff of 2.92 providing 81.3% sensitivity and 79.1-80.2% specificity for HCC diagnosis. The inter-reader agreement for SMI patterns had a kappa score of 0.634, while the intraclass correlation coefficient (ICC) for VI values was 0.959.ConclusionHCCs displayed more hypervascular SMI patterns and significantly higher VI values compared to other malignant FLLs, emphasizing the diagnostic potential of VI in distinguishing HCC from non-HCC tumors. Although metastases primarily exhibited hypovascular patterns and low VI values, no dominant vascular pattern was identified in non-HCC primary liver malignancies. Assessing VI values provided higher interobserver agreement compared to SMI patterns, enhancing objectivity and reproducibility.en_US
dc.description.sponsorshipScientific and Technological Research Council of Tuerkiye (TUEBITAK)en_US
dc.description.sponsorshipThis research is funded by the Scientific and Technological Research Council of Tuerkiye (TUEBITAK). The authors did not receive support from any organization for the submitted worken_US
dc.identifier.citationAslan, H. S., Arslan, M., Alver, K. H., Vurgun, S., Demirci, M. ve Tekinhatun, M. (2024). Role of Superb Microvascular Imaging (SMI) vascularity index values and vascularity patterns in the differential diagnosis of malignant liver lesions. Abdominal Radiology, 1-14.
dc.identifier.doi10.1007/s00261-024-04711-z
dc.identifier.issn2366-004X
dc.identifier.issn2366-0058
dc.identifier.pmid39576317en_US
dc.identifier.scopus2-s2.0-85210023932en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00261-024-04711-z
dc.identifier.urihttps://hdl.handle.net/11468/29803
dc.identifier.wosWOS:001360954400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTekinhatun, Muhammed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAbdominal Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectSuperb microvascular imaging (SMI)en_US
dc.subjectSMI vascular paternen_US
dc.subjectSMI vascularity index (VI)en_US
dc.subjectMalignant focal liver lesionen_US
dc.subjectInterobserver agreementen_US
dc.titleRole of Superb Microvascular Imaging (SMI) vascularity index values and vascularity patterns in the differential diagnosis of malignant liver lesionsen_US
dc.typeArticleen_US

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