Hematological predictors of silent new cerebral ischemic lesions in carotid artery stenting: A retrospective study

Basit Öğe Kaydı
dc.authoridSAHIN, ANIL/0000-0003-1956-2348
dc.authoridAKTEMUR, TUGBA/0000-0002-5578-432X
dc.authoridaltunova, Mehmet/0000-0001-5351-5022
dc.authoridDemir, Yusuf/0000-0001-9167-493X
dc.contributor.authorAltunova, Mehmet
dc.contributor.authorDemir, Yusuf
dc.contributor.authorGulmez, Recep
dc.contributor.authorEvsen, Ali
dc.contributor.authorAktemur, Tugba
dc.contributor.authorSahin, Ahmet Anil
dc.contributor.authorArslan, Enes
dc.date.accessioned2025-02-22T14:09:01Z
dc.date.available2025-02-22T14:09:01Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Silent new cerebral ischemic lesions (sNCIL) are a common complication of carotid artery stenting (CAS) that can lead to an increase in morbidity and mortality. We aimed to evaluate the impact of hematological parameters on sNCIL in patients undergoing CAS. Methods: We retrospectively evaluated 103 patients who underwent CAS, with a mean age of 70.5 +/- 6.7 years, and 31 (20.1 %) of whom were female. Stents were placed for internal carotid artery revascularization. The presence of new hyperintense lesions on diffusion-weighted imaging (DWI) without neurological symptoms was considered as sNCIL in cases without apparent neurological findings. Patients were categorized into two groups based on DWI results: positive (29) and negative (74). Results: In the study population, sNCIL was observed in 29 patients (28.2 %). The DWI-positive group exhibited significantly higher Plateletcrit (PCT) levels, advanced age, and a lack of embolic protection device usage compared to the DWI-negative group. The Receiver Operating Characteristic (ROC) analysis identified a PCT value of 0.26 as the optimal threshold, detecting the development of sNCIL with a sensitivity of 75.9 % and specificity of 59.1 % (AUC: 0.700; 95 % CI: 0.594 -0.806, p = 0.002). Conclusion: To be determined by a simple blood parameter, PCT can predict the risk of sNCIL before CAS and holds clinical value in the treatment of patients with carotid artery stenosis.en_US
dc.identifier.doi10.1016/j.jocn.2024.04.002
dc.identifier.endpage35en_US
dc.identifier.issn0967-5868
dc.identifier.issn1532-2653
dc.identifier.pmid38640806en_US
dc.identifier.scopus2-s2.0-85190721636en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage30en_US
dc.identifier.urihttps://doi.org/10.1016/j.jocn.2024.04.002
dc.identifier.urihttps://hdl.handle.net/11468/29755
dc.identifier.volume124en_US
dc.identifier.wosWOS:001233406100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofJournal of Clinical Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectCarotid arteryen_US
dc.subjectStentingen_US
dc.subjectDiffusion-weighted imagingen_US
dc.subjectPlateletcriten_US
dc.subjectSilent new ischemic cerebral lesionsen_US
dc.titleHematological predictors of silent new cerebral ischemic lesions in carotid artery stenting: A retrospective studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu