Intra-peritoneal administration of Ecballium elaterium diminishes postoperative adhesions

dc.authorid0000-0002-6720-1515en_US
dc.authorid0000-0003-1385-9415en_US
dc.authorid0000-0003-4551-8439en_US
dc.contributor.authorOkur, Mehmet Hanifi
dc.contributor.authorAydoğdu, Bahattin
dc.contributor.authorArslan, Mehmet Şerif
dc.contributor.authorAlabalık, Ulaş
dc.contributor.authorArslan, Serkan
dc.contributor.authorKara, İbrahim
dc.contributor.authorCanpolat, Fethiye
dc.contributor.authorŞahin, Atalay
dc.contributor.authorOtçu, Selçuk
dc.date.accessioned2023-10-27T11:06:34Z
dc.date.available2023-10-27T11:06:34Z
dc.date.issued2014en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Çocuk Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractRESULTS: The adhesion score was significantly decreased in the EE group (p=0.001) in comparison with the control group. Microscopically, the EE and sham groups were significantly lower than that of the control group (p[removed] METHODS: Thirty rats were divided into three groups and underwent midline laparotomy under 35 mg/kg ketamine and 5 mg/kg xylazine anaesthesia. In group 1 (n=10), the sham operation group, the abdominal walls were closed without any process. In group 2 (n=10), the control group, the antimesenteric border of the ceacum and the corresponding parietal peritoneum were abraded with dry sterile gauze. In group 3 (n=10), the EE group, 2.5 mg/kg dose of EE was administered as intraperitoneally to the rats after abrasion. All rats were sacrificed on postoperative day 15. Samples were obtained. CONCLUSION: The grade and severity of abdominal adhesion could be significantly reduced through administered Ecballium elaterium and therefore be a suitable anti-inflammatory agent for the prevention of postoperative peritoneal adhesion in the future. PURPOSE: To evaluate the effects of Ecballium elaterium (EE), Elaterium officinarum, in postoperative intraperitoneal adhesions in rats.en_US
dc.identifier.citationOkur, M. H., Aydoğdu, B., Arslan, M. Ş., Alabalık, U., Arslan, S., Kara, İ. ve diğerleri. (2014). Intra-peritoneal administration of Ecballium elaterium diminishes postoperative adhesions. Acta Cirurgica Brasileira, 29(10), 639-643.en_US
dc.identifier.doi10.1590/S0102-8650201400160003
dc.identifier.endpage643en_US
dc.identifier.issn0102-8650
dc.identifier.issue10en_US
dc.identifier.pmid25317995
dc.identifier.scopus2-s2.0-84908072355
dc.identifier.scopusqualityQ2
dc.identifier.startpage639en_US
dc.identifier.urihttps://www.scielo.br/j/acb/a/kjZtMf3F8tKRZyqnPLchhmQ/?lang=en
dc.identifier.urihttps://hdl.handle.net/11468/12983
dc.identifier.volume29en_US
dc.identifier.wosWOS:000343982100003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorOkur, Mehmet Hanifi
dc.institutionauthorAydoğdu, Bahattin
dc.institutionauthorArslan, Mehmet Şerif
dc.institutionauthorAlabalık, Ulaş
dc.institutionauthorArslan, Serkan
dc.institutionauthorKara, İbrahim
dc.institutionauthorCanpolat, Fethiye
dc.institutionauthorŞahin, Atalay
dc.institutionauthorOtçu, Selçuk
dc.language.isoenen_US
dc.publisherSociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgiaen_US
dc.relation.ispartofActa Cirurgica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdhesionen_US
dc.subjectAnti-inflammatory agentsen_US
dc.subjectElaterium officinarumen_US
dc.subjectPeritoneumen_US
dc.subjectRatsen_US
dc.titleIntra-peritoneal administration of Ecballium elaterium diminishes postoperative adhesionsen_US
dc.titleIntra-peritoneal administration of Ecballium elaterium diminishes postoperative adhesions
dc.typeArticleen_US

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