Pancreas survival in simultaneous pancreas-kidney and pancreas-after-kidney transplantations: A five-year follow-up report

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dc.contributor.authorDinckan, Ayhan
dc.contributor.authorAliosmanoglu, Ibrahim
dc.contributor.authorKocak, Huseyin
dc.contributor.authorSari, Ramazan
dc.contributor.authorErdogan, Okan
dc.contributor.authorErtug, Zeki
dc.contributor.authorSuleymanlar, Gultekin
dc.date.accessioned2024-04-24T17:37:44Z
dc.date.available2024-04-24T17:37:44Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Pancreas transplantation methods, such as simultaneous pancreas-kidney (SPK) transplantation and pancreas-after-kidney (PAK) transplantation, have become the most important treatments for patients with type-1 diabetes mellitus (DM)-related end-stage renal diseases (ESRD). The purpose of the study was to compare the clinical results of the pancreas graft in patients after SPK and PAK transplantations and to present the findings of our 5-year follow-up. Material/Method: A total of 55 patients who had kidney and pancreas transplantation between February 2003 and December 2010 were included in the study. The patients were divided into 2 groups based on the timing of the pancreas transplantation: SPK (n=21) and PAK (n=34). Result: The patients in the SPK group consisted of 13 males and 8 females, with a mean age of 33.6 +/- 6.8 years; whereas 25 males and 9 females formed the PAK group, with a mean age of 32.0 +/- 6.0 years. In the early postoperative period, the SPK group had 3 patients with vascular thrombosis (2 venous, 1 arterial) and the PAK group had 7 patients with thrombosis (4 venous, 3 arterial) (p=0.319). At the end of the 5-year follow-up, the patient, kidney and pancreas survival rates in the SPK group were 95.2%, 95.2%, and 61.9% respectively, and the corresponding values in the PAK group were 97%, 91.2%, 61.8% (p=0.382, p=0.504, p=0.927). Conclusions: We concluded that PAK is just as effective as SPK to prevent the destructive effects of DM when the waiting time for SPK is long and a potential live donor is present.en_US
dc.identifier.endpage19en_US
dc.identifier.issn1425-9524
dc.identifier.issue3en_US
dc.identifier.pmid23018251
dc.identifier.scopus2-s2.0-84868691486
dc.identifier.scopusqualityQ2
dc.identifier.startpage14en_US
dc.identifier.urihttps://hdl.handle.net/11468/21149
dc.identifier.volume17en_US
dc.identifier.wosWOS:000325185900002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt Scientific Literature, Incen_US
dc.relation.ispartofAnnals of Transplantation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPancreas Transplantationen_US
dc.subjectKidney Transplantationen_US
dc.subjectSurvivalen_US
dc.titlePancreas survival in simultaneous pancreas-kidney and pancreas-after-kidney transplantations: A five-year follow-up reporten_US
dc.titlePancreas survival in simultaneous pancreas-kidney and pancreas-after-kidney transplantations: A five-year follow-up report
dc.typeArticleen_US

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