Type 4 Renal Tubular Acidosis in a Patient With Lupus Nephritis
[ X ]
Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Iranian Soc Nephrolgy
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Although renal tubular acidosis (RTA) is a rare complication of systemic lupus erythematosus (SLE), type 4 RTA associated with lupus nephritis is extremely rare. A 20-year-old woman presented with malaise and edema in the lower extremities and face. She had multiple lymphadenopathies. There were 20% eosinophil in blood smear and 32% in bone marrow aspiration. Serology revealed positive antinuclear antibody at 1:1000 titer, positive double-stranded DNA antibodies, and low complements C3 and C4 levels. Urinary sediment was active and urinary protein excretion was 4.8 g/d. The SLE Disease Activity Index score was 23. A high SLE Disease Activity Index scores was proposed as a potential risk factor for type 4 RTA. Type 4 RTA may complicate SLE, and specifically, patients with high SLEDAI scores and lymphadenopathy may pose a high risk. Our patient responded successfully to immunomodulatory therapy.
Açıklama
Anahtar Kelimeler
Renal Tubular Acidosis, Systemic Lupus Erythematosus, Eosinophilia
Kaynak
Iranian Journal of Kidney Diseases
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
8
Sayı
1
