Localization of estrogen receptor ? and progesterone receptor B in bovine cervix and vagina during the follicular and luteal phases of the sexual cycle

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dc.contributor.authorSagsoz, H.
dc.contributor.authorAkbalik, M. E.
dc.contributor.authorSaruhan, B. G.
dc.contributor.authorKetani, M. A.
dc.date.accessioned2024-04-24T17:20:30Z
dc.date.available2024-04-24T17:20:30Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe localization and distribution of estrogen receptors (ER a) and progesterone receptors (PR-B) in the cervix and vagina of sexually mature bovines during the follicular and luteal phases of the sexual cycle were studied using immunohistocehmistry. The estrous cycle stage of 23 Holstein bovines was assessed by gross and histological appearance of ovaries and blood steroid hormone values. Tissue samples from cervix and vagina were fixed in 10% formaldehyde for routine histological processing. Nuclear staining for ER a and PR-B was observed in the epithelial cells of the surface epithelium, stromal cells and smooth muscle cells. Generally, in the cervix, ER a immunoreactivity was more intense in the epithelial and smooth muscle cells during the follicular phase and in the epithelial cells during the luteal phase (p < 0.05). PR-B immunoreactivity was more intense in the epithelial and smooth muscle cells than in the superficial and deep stromal cells during the follicular and luteal phases (p < 0.05). In the vagina, ER a and PR-B immunoreactivities were more intense in the epithelial cells than in the connective tissue cells and smooth muscle cells during the follicular and luteal phases (p < 0.05). These results indicated that the frequency and intensity of ER a and PR-B immunoreactivity in the cervix and vagina of bovines varied according to the cervical and vaginal cell types and the phases of the sexual cycle.en_US
dc.identifier.doi10.3109/10520291003795861
dc.identifier.endpage271en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue4en_US
dc.identifier.pmid20438296
dc.identifier.scopus2-s2.0-79960453595
dc.identifier.scopusqualityQ2
dc.identifier.startpage262en_US
dc.identifier.urihttps://doi.org/10.3109/10520291003795861
dc.identifier.urihttps://hdl.handle.net/11468/19096
dc.identifier.volume86en_US
dc.identifier.wosWOS:000292779100006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnic & Histochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBovineen_US
dc.subjectCervixen_US
dc.subjectEstrogen Receptoren_US
dc.subjectProgesterone Receptoren_US
dc.subjectVaginaen_US
dc.titleLocalization of estrogen receptor ? and progesterone receptor B in bovine cervix and vagina during the follicular and luteal phases of the sexual cycleen_US
dc.titleLocalization of estrogen receptor ? and progesterone receptor B in bovine cervix and vagina during the follicular and luteal phases of the sexual cycle
dc.typeArticleen_US

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