Renal amyloidosis in cattle with inflammatory diseases

Basit Öğe Kaydı
dc.contributor.authorElitok, O. M.
dc.contributor.authorElitok, B.
dc.contributor.authorUnver, O.
dc.date.accessioned2024-04-24T17:11:41Z
dc.date.available2024-04-24T17:11:41Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: The association of inflammatory diseases such as traumatic reticuloperitonitis (TRP), mastitis, metritis, and pododermatitis with renal amyloidosis in cattle is poorly described. Hypothesis: Serum amyloid A (SAA) levels are elevated during inflammatory diseases, and renal amyloidosis is formed as a complication. Animals: This study was conducted with 82 crossbred cattle with mastitis (n = 18 cows), metritis (n = 11 cows), TRP (n = 30 cows), and pododermatitis (n = 23 : 15 cows and 8 beef cattle). Ten clinically healthy cows served as controls. Methods: Hematological, urinary, and blood parameters, including SAA, were measured by an automated procedure provided with trade kits. Determination of amyloidal structures was made by histopathological examination of renal biopsy specimens. Results: At the end of this trial, amyloidosis was detected in 5 cows displaying typical nephrotic syndrome, with hypoproteinemia and proteinuria in combination with polyuria and weight loss. Furthermore, it was observed that cows with renal amyloidosis had significantly higher (P < .01) total leukocyte counts, serum and urine enzyme activities, and urea and creatinine concentrations, with lower serum total protein concentrations, when compared with animals without renal amyloidosis. Conclusions and Clinical Importance: The incidence of AA amyloidosis in cattle in this study suggests that cattle with mastitis, metritis, and pododermatitis have a high prevalence of systemic amyloidosis in response to inflammation.en_US
dc.identifier.doi10.1111/j.1939-1676.2008.0059.x
dc.identifier.endpage455en_US
dc.identifier.issn0891-6640
dc.identifier.issue2en_US
dc.identifier.pmid18312553
dc.identifier.scopus2-s2.0-42449104418
dc.identifier.scopusqualityQ1
dc.identifier.startpage450en_US
dc.identifier.urihttps://doi.org/10.1111/j.1939-1676.2008.0059.x
dc.identifier.urihttps://hdl.handle.net/11468/17676
dc.identifier.volume22en_US
dc.identifier.wosWOS:000254416100031
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofJournal of Veterinary Internal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBovineen_US
dc.subjectInflammationen_US
dc.subjectRenal Amyloidosisen_US
dc.subjectSerum Amyloid Aen_US
dc.titleRenal amyloidosis in cattle with inflammatory diseasesen_US
dc.titleRenal amyloidosis in cattle with inflammatory diseases
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu