Study of aqueous ecballium elaterium as fibrinolytic in the rabbit model of intrapleural empyema

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dc.authorid0000-0003-4551-8439en_US
dc.contributor.authorŞahin, A.
dc.contributor.authorOruç, M.
dc.contributor.authorMeteroğlu, F.
dc.contributor.authorErbey, A.
dc.contributor.authorAlabalık, U.
dc.contributor.authorKaplan, I.
dc.date.accessioned2022-02-21T12:53:17Z
dc.date.available2022-02-21T12:53:17Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.descriptionWOS:000751358000011
dc.descriptionPMID: 34531345
dc.description.abstractAims: We aimed to investigate of intrapleural use of ecballium elaterium (EE) in a rabbit model empyema. Methods: An empyema was induced in 21 rabbits after inoculation of Staphylococcus aureus. Glucose levels, pH, lactate dehydrogenase levels, and amounts of pleural drainage were evaluated in addition to pleural and empyema scores. The rabbits were divided into three groups, each 7, the isotonic solution, the streptokinase, and the ecballium group. Results: At autopsy, there was no difference in pH, glucose, and LDH levels in three groups. The mean pleural drainage was greater in the ecballium group. A significant difference was detected between groups in terms of drainage amounts and pleural and empyema scores (P < 0.05). A significant difference in pleural and empyema scores was detected in the ecballium and streptokinase groups (P < 0.05). EE group had significant differences in drainage amounts and plural and empyema scores regard to the control group (P < 0.05). No significance was found between streptokinase and EE groups. Conclusion: We conclude that intrapleural use of EE is at least as effective as streptokinase for the treatment of empyema.en_US
dc.identifier.citationŞahin, A., Oruç, M., Meteroğlu, F., Erbey, A ., Alabalık, U. ve Kaplan, I. (2021). Study of aqueous ecballium elaterium as fibrinolytic in the rabbit model of intrapleural empyema. Nigerian Journal of Clinical Practice, 24(9), 1326-1331.en_US
dc.identifier.doi10.4103/njcp.njcp_360_20
dc.identifier.endpage1331en_US
dc.identifier.issn1119-3077
dc.identifier.issue9en_US
dc.identifier.pmid34531345
dc.identifier.scopus2-s2.0-85115844130
dc.identifier.scopusqualityQ2
dc.identifier.startpage1326en_US
dc.identifier.urichrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/viewer.html?pdfurl=https%3A%2F%2Fwww.njcponline.com%2Ftemp%2FNigerJClinPract2491326-3901385_105013.pdf&clen=878908&chunk=true
dc.identifier.urihttps://hdl.handle.net/11468/9195
dc.identifier.volume24en_US
dc.identifier.wosWOS:000751358000011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAlabalık, U.
dc.institutionauthorKaplan, I.
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEcballiumen_US
dc.subjectEmpyemaen_US
dc.subjectFibrinolyticsen_US
dc.subjectStreptokinaseen_US
dc.titleStudy of aqueous ecballium elaterium as fibrinolytic in the rabbit model of intrapleural empyemaen_US
dc.titleStudy of aqueous ecballium elaterium as fibrinolytic in the rabbit model of intrapleural empyema
dc.typeArticleen_US

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