A novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional study

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dc.contributor.authorDemir, Muhammed
dc.contributor.authorOzbek, Mehmet
dc.date.accessioned2024-04-24T17:18:08Z
dc.date.available2024-04-24T17:18:08Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: Severe inflammation is reportedly associated with subsequent cardiovascular events, including in patients with coronary artery disease. This study aimed to examine the prognostic value of systemic immune-inflammation index and determine mortality and clinical outcomes in patients with chronic coronary total occlusion. METHODS: Our study evaluated 366 consecutive coronary total occlusion patients. The clinical end points were all-cause mortality and major adverse cardiovascular events, which include target vessel revascularization, myocardial infarction, and cerebrovascular events during 105 months follow-up. RESULTS: The study findings showed 59 (16.1%) all-cause death, 22 (6%) target vessel revascularization cases, 32 (8.7%) myocardial infarction cases, and 13 (3.6%) cerebrovascular events cases, with a median follow-up of 49 months (26-74). Multivariate logistic regression analysis showed that systemic immune-inflammation index was not associated with target vessel revascularization, myocardial infarction, and cerebrovascular events. Multivariate Cox regression analysis found systemic immune-inflammation index to be associated with all-cause death. Kaplan-Meier analysis showed a lower survival rate and myocardial infarction-free survival time in patients with higher systemic immune-inflammation index scores. CONCLUSION: Although systemic immune-inflammation index is a preferable tool for the detection of mortality, it failed to give adverse outcomes. Larger multicenter studies are thus warranted to investigate the effect of systemic immune-inflammation index on clinical outcomes.en_US
dc.identifier.doi10.1590/1806-9282.20211097
dc.identifier.endpage585en_US
dc.identifier.issn1806-9282
dc.identifier.issue5en_US
dc.identifier.pmid35584478
dc.identifier.scopus2-s2.0-85130304296
dc.identifier.scopusqualityQ2
dc.identifier.startpage579en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20211097
dc.identifier.urihttps://hdl.handle.net/11468/18625
dc.identifier.volume68en_US
dc.identifier.wosWOS:000800366600008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInflammationen_US
dc.subjectInflammation Mediatorsen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectPrognosisen_US
dc.subjectAtherosclerosisen_US
dc.titleA novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional studyen_US
dc.titleA novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional study
dc.typeArticleen_US

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