Is 18F-FDG-PET/CT prognostic factor for survival in patients with small cell lung cancer? Single center experience

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dc.contributor.authorInal, A.
dc.contributor.authorKucukoner, M.
dc.contributor.authorKaplan, M. A.
dc.contributor.authorUrakci, Z.
dc.contributor.authorNas, N.
dc.contributor.authorGuven, M.
dc.contributor.authorDostbil, Z.
dc.date.accessioned2024-04-24T17:37:35Z
dc.date.available2024-04-24T17:37:35Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Although a number of studies in patients with a variety of malignant tumors have shown that metabolic activity on fluorine-18 deoxyglucose positron emission tomography computed tomography (F-18-FDG-PET/CT) is correlated with survival, there are few studies about the impact of F-18-FDG-PET/CT for survival in small cell lung cancer (SCLC) patients. There is still some ambiguity as to whether FDG PET in patients with SCLC will ensure prognostic knowledge for survival. We performed a retrospective analysis of prognostic implication of F-18-FDG-PET/CT in patients with SCLC. Methods: We retrospectively reviewed 54 patients with histologically or cytologically proven SCLC who had undergone pre-treatment F-18-FDG-PET/CT scanning between September 2007 and November 2011 in the Dicle University, School of Medicine, Department of Medical Oncology. SUVmax and other potential prognostic variables were chosen for analysis in this study. Univariate and multivariate analyses were conducted to identify prognostic factors associated with survival. Result: Among the eleven variables of univariate analysis, three variables were identified as having prognostic significance: Performance status (p < 0.001), stage (p = 0.02) and diabetes mellitus (p =0.05). Multivariate analysis showed that performance status and stage were considered independent prognostic factors for survival (p< 0.001 and p- 0.002 respectively). Conclusion: In conclusion, performance status and stage were identified as important prognostic factors, while F-18-FDG-PET/CT uptake of the primary lesions was not associated with prognostic importance for survival in patients with SCLC. (C) 2012 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L. All rights reserved.en_US
dc.identifier.endpage265en_US
dc.identifier.issn0873-2159
dc.identifier.issue6en_US
dc.identifier.pmid23993406
dc.identifier.scopus2-s2.0-84888350333
dc.identifier.scopusqualityN/A
dc.identifier.startpage260en_US
dc.identifier.urihttps://hdl.handle.net/11468/21044
dc.identifier.volume19en_US
dc.identifier.wosWOS:000330117700005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Espana Sluen_US
dc.relation.ispartofRevista Portuguesa De Pneumologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmall Cell Lung Canceren_US
dc.subjectPrognostic Factorsen_US
dc.subjectF-18-Fdg-Pet/Cten_US
dc.titleIs 18F-FDG-PET/CT prognostic factor for survival in patients with small cell lung cancer? Single center experienceen_US
dc.titleIs 18F-FDG-PET/CT prognostic factor for survival in patients with small cell lung cancer? Single center experience
dc.typeArticleen_US

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