The comparison of amino-terminal probrain natriuretic peptide levels in preeclampsia and normotensive pregnancy

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dc.contributor.authorKale, A
dc.contributor.authorKale, E
dc.contributor.authorYalinkaya, A
dc.contributor.authorAkdeniz, N
dc.contributor.authorCanoruç, N
dc.date.accessioned2024-04-24T17:18:01Z
dc.date.available2024-04-24T17:18:01Z
dc.date.issued2005
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to evaluate the levels of amino-terminal probrain natriuretic peptide (Nt pro-BNP) in preeclampsia in comparison with normotensive pregnancy. Materials and methods: Women with preeclampsia (proteinuria >= 300 mg/24 In and at least two readings of systolic blood pressure >= 140 mm Hg and diastolic blood pressure >= 90 mm Hg) (n=32 mild preeclampsia and n=8 severe preeclampsia) were compared with normotensive women (n=40). Serum Nt pro-BNP was measured using an electrochemiluminescence immunoassay (ECLIA) method (Nt pro-BNP, Roche) with a Roche modular analytics E170 immunoassay analyzer. Statistical analysis was carried out by the Student t-test, and a P value of <0.05 was accepted as statistically significant. Results: The median serum Nt pro-BNP was 430 +/- 28.91 pg/mL in preeclampsia. The levels of serum Nt pro-BNP were 74 16.82 pg/mL in normotensive pregnant women (P < 0.001) and significantly higher in women with preeclampsia (P < 0.001). Conclusion: The higher levels of serum Nt pro-BNP in preeclamptic women may be an indicator of high left-ventricular filling pressure, and indicate left-ventricular diastolic dysfunction.en_US
dc.identifier.doi10.1515/JPM.2005.023
dc.identifier.endpage124en_US
dc.identifier.issn0300-5577
dc.identifier.issn1619-3997
dc.identifier.issue2en_US
dc.identifier.pmid15843261
dc.identifier.scopus2-s2.0-16444369297
dc.identifier.scopusqualityQ1
dc.identifier.startpage121en_US
dc.identifier.urihttps://doi.org/10.1515/JPM.2005.023
dc.identifier.urihttps://hdl.handle.net/11468/18536
dc.identifier.volume33en_US
dc.identifier.wosWOS:000228062300007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal of Perinatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmino-Terminal Probrain Natriuretic Peptide (Nt Pro-Bnp)en_US
dc.subjectNormotensive Pregnancyen_US
dc.subjectPreeclampsiaen_US
dc.titleThe comparison of amino-terminal probrain natriuretic peptide levels in preeclampsia and normotensive pregnancyen_US
dc.titleThe comparison of amino-terminal probrain natriuretic peptide levels in preeclampsia and normotensive pregnancy
dc.typeArticleen_US

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