Prevalence of Hepatitis C in adults in the south-eastern region of Anatolia

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dc.contributor.authorDursun, M
dc.contributor.authorÖzekinci, T
dc.contributor.authorErtem, M
dc.contributor.authorSaka, G
dc.contributor.authorYilmaz, S
dc.contributor.authorCanoruc, F
dc.contributor.authorÇelenk, S
dc.date.accessioned2024-04-24T16:14:51Z
dc.date.available2024-04-24T16:14:51Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: There is a limited number of studies on the general population about prevalence of Hepatitis C virus (HCV) in Turkey. The estimated prevalence of HCV in the Southeastern region of the country was obtained from the data of the blood donors. There is no study reflecting the general population of this region, leading us to plan this study. Material and method: Four provinces in the Southeastern Anatolia were randomly selected and sample sizes were determined by Epi Info Programme, and blood samples were collected from 2888 individuals. Questionnaires in which demographic information and probable risk factors for Hepatitis C were investigated and were applied on subjects who gave their consent to participate in the study. Anti-HCV was examined by using Cobas Core II immunochemistry system (Roche). All positive samples were further tested for the presence of HCV RNA by RT-PCR. Crude odds ratios (OR) and 95% confidence intervals (CI) were calculated and Chi-square analyses were performed. Epi Info 2000 Programme was used to perform the analysis. Results: Of the 2888 individuals, 17 (0.6%) were anti-HCV positive and 13 (82%) of them were confirmed as positive for HCV-RNA. No difference was found between rural and urban regions with respect to HCV prevalence (P = 0.51). The prevalence of HCV in 35-44 years of age group was found to be different from those of the other age groups (P = 0.02). It was determined that the risk for HCV in this age group was 4.23 times (P = 0.02; OR = 4.23;1.02-20.15; CI 95%:) higher with a prevalence rate of 1.6%. In this age group, anti-HCV was positive in 6 male (2.4%) and 2 female (0.8%), of whom 7 were living in urban (2.2%) and 1 in rural area (0.5%). The overall prevalence of HCV was not found to be different for sex (P = 0.75). Similarly, there was no difference between the married and single individuals for the prevalence (P = 0.38). Anti-HCV positivity did not change for the level of education. We could not determine any factor that might play a role in transmission of HCV. Conclusion: This is the first population-based study to be performed in order to determine the prevalence of HCV in the south-eastern region of Anatolia (Turkey). This region has a low prevalence of HCV. The extremely rare prevalence of homosexuality and intravenous drug addiction might have a role in this low prevalence. (C) 2004 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.hepres.2004.02.012
dc.identifier.endpage80en_US
dc.identifier.issn1386-6346
dc.identifier.issn1872-034X
dc.identifier.issue2en_US
dc.identifier.pmid15163428
dc.identifier.scopus2-s2.0-2442642896
dc.identifier.scopusqualityQ1
dc.identifier.startpage75en_US
dc.identifier.urihttps://doi.org/10.1016/j.hepres.2004.02.012
dc.identifier.urihttps://hdl.handle.net/11468/15447
dc.identifier.volume29en_US
dc.identifier.wosWOS:000222432400002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofHepatology Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis C Virusen_US
dc.subjectPrevalenceen_US
dc.titlePrevalence of Hepatitis C in adults in the south-eastern region of Anatoliaen_US
dc.titlePrevalence of Hepatitis C in adults in the south-eastern region of Anatolia
dc.typeArticleen_US

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