The expressions of some metabolic hormones (leptin, ghrelin and obestatin) in the tissues of sheep tongue

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dc.contributor.authorSagsoz, Hakan
dc.contributor.authorErdogan, Serkan
dc.contributor.authorSaruhan, Berna Guney
dc.date.accessioned2024-04-24T17:11:25Z
dc.date.available2024-04-24T17:11:25Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this study, we aimed to observe the localization and expression of peptide hormones-leptin, ghrelin and obestatin-in the sheep tongue by immunohistochemistry. For that purpose, tongues of ten adult sheep were used. Leptin expression of moderate intensity was observed in the basal and parabasal epithelial cells of the luminal epithelium, and leptin was strongly expressed in the taste buds of the circumvallate and fungiform papillae and in von Ebner's glands. Ghrelin was primarily expressed in some of the skeletal muscle cells and the smooth muscle cells of the middle layer of blood vessels. A strong expression was observed in the epithelial cells lining the base of the groove surrounding the circumvallate papillae. Obestatin expression was particularly strong in the epithelial cells of the salivary ducts. It was also stronger in the von Ebner's glands than in the seromucous glands. Leptin, ghrelin and obestatin were shown to be produced at varying levels in different cell types, including epithelial, stromal and skeletal muscle cells, as well as in ganglion neurons, neural plexuses and blood vessels in the sheep tongue. Cellular localization and expression of these peptide hormones have not been investigated in many species including sheep.en_US
dc.identifier.doi10.1111/ahe.12499
dc.identifier.endpage120en_US
dc.identifier.issn0340-2096
dc.identifier.issn1439-0264
dc.identifier.issue1en_US
dc.identifier.pmid31568599
dc.identifier.scopus2-s2.0-85073995343
dc.identifier.scopusqualityQ2
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.1111/ahe.12499
dc.identifier.urihttps://hdl.handle.net/11468/17490
dc.identifier.volume49en_US
dc.identifier.wosWOS:000488192800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnatomia Histologia Embryologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHormoneen_US
dc.subjectImmunohistochemistryen_US
dc.subjectSheepen_US
dc.subjectTongueen_US
dc.titleThe expressions of some metabolic hormones (leptin, ghrelin and obestatin) in the tissues of sheep tongueen_US
dc.titleThe expressions of some metabolic hormones (leptin, ghrelin and obestatin) in the tissues of sheep tongue
dc.typeArticleen_US

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