Comparison of lornoxicam versus tramadol analgesia for transrectal prostate biopsy: a randomized prospective study

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dc.contributor.authorOlmez, Gonul
dc.contributor.authorKaya, Sedat
dc.contributor.authorAflay, Ugur
dc.contributor.authorSahin, Hayrettin
dc.date.accessioned2024-04-24T16:02:24Z
dc.date.available2024-04-24T16:02:24Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction We compared the efficacy of lornoxicam and tramadol to provide analgesia and comfort during transrectal ultrasound-guided biopsy of the prostate (TRUSP) as a noninvasive method. Materials and methods A total of 62 men undergoing TRUSP were enrolled in this study. Patients were randomized to three groups. Group 1 (n = 21) received 8 mg of lornoxicam, group 2 (n = 21) received 100 mg of tramadol, and group 3 (n = 20) received saline as a control. The drugs were given intramuscularly half an hour prior to the procedure. All patients were asked to indicate the level of pain experienced after the procedure by visual analog score (VAS), and the patient's comfort level was scored by a comfort score. Additionally, the patients were asked if they were willing to undergo a. future TRUSP. Results The data obtained revealed that both experimental groups receiving lornoxicam and tramadol had lower VAS scores compared to the control group (3.4 and 2.4 vs. 6.4, respectively; P < 0.0001). There were also significant differences in VAS scores between group 1 and group 2 (P = 0.027). There was a significant difference in the comfort score between the drug groups and control (P > 0.0001) and between the lornoxicam and tramadol group (P < 0.05). Pain and discomfort were least in the tramadol group. The percentage of patients who would not consent to future TRUSP was lower in the drug groups compared to control (P < 0.0001). But there were not any differences between the drug groups. Conclusions The use of lornoxicam or tramadol for pain relief in TRUSP is a practical, effective and comfortable method compared to the results of the control group. In addition, tramadol was found to be more effective than lornoxicam.en_US
dc.identifier.doi10.1007/s11255-007-9297-4
dc.identifier.endpage344en_US
dc.identifier.issn0301-1623
dc.identifier.issue2en_US
dc.identifier.pmid17999159
dc.identifier.scopus2-s2.0-52649105355
dc.identifier.scopusqualityQ2
dc.identifier.startpage341en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-007-9297-4
dc.identifier.urihttps://hdl.handle.net/11468/14781
dc.identifier.volume40en_US
dc.identifier.wosWOS:000256194700016
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology and Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProstateen_US
dc.subjectBiopsyen_US
dc.subjectPainen_US
dc.subjectTramadolen_US
dc.subjectLornoxicamen_US
dc.titleComparison of lornoxicam versus tramadol analgesia for transrectal prostate biopsy: a randomized prospective studyen_US
dc.titleComparison of lornoxicam versus tramadol analgesia for transrectal prostate biopsy: a randomized prospective study
dc.typeArticleen_US

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