Comprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn.

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dc.authorid0000-0001-8340-3347en_US
dc.authorid0000-0002-1569-2535en_US
dc.authorid0000-0003-4541-1893en_US
dc.authorid0000-0002-4090-7227en_US
dc.authorid0000-0001-6548-7823en_US
dc.authorid0000-0003-4163-9962en_US
dc.contributor.authorKayıran, Serpil Demirci
dc.contributor.authorÖzkan, Esra Eroğlu
dc.contributor.authorKara, Emel Mataracı
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorZengin, Gökhan
dc.contributor.authorBoğa, Mehmet
dc.date.accessioned2023-10-25T11:45:05Z
dc.date.available2023-10-25T11:45:05Z
dc.date.issued2019en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractThe study was aimed to investigate the phenolic compounds of Allium macrochaetum by LC-MS/MS, as well as the antioxidant, antialzheimer, and antimicrobial activities of the extracts, and determination of the essential oil and fatty acid compositions by GC-MS. The results indicate that malic acid and t-caffeic acid are the major compounds in the bulbs. The main components of fatty acids were found to be linolenic (40.72%), oleic (19.79%), and palmitic (18.45%) acids. The allyl disulfide (66.97%) was found as major compound in the essential oil. The ethanol extract of the bulbs exhibited stronger ABTS cation (IC50: 55.90 ± 1.08 µg/ml) and DPPH free (IC50: 204.43 ± 2.17 µg/ml) radical scavenging activities than the other extracts. The extract also showed moderate cupric reducing activity with 1.52 absorbance at 100 µg/ml concentration. Only the ethanol extract of the bulbs showed weak inhibition (23.34 ± 0.11%) against butrylcholinesterase enzyme at 200 µg/ml. Practical applications: Allium macrochaetum is a wild and edible garlic species which grown in Turkey, Iran, Iraqi, and Syria. A. macrochaetum has been used by local people in Turkish folk medicine as an antibiotic, and for the treatment of alopecia. The health benefits and nutritional values of A. macrochaetum were clarified in the first time. Phenolic compounds of A. macrochaetum were detected by LC-MS/MS. The essential oil and fatty acid compositions of A. macrochaetum were identified by GC-MS. Antioxidant, antialzheimer, and antimicrobial activities potential of A. macrochaetum were determined.en_US
dc.description.sponsorshipCukurova University TSA-2016-5160
dc.identifier.citationKayıran, S. D., Özkan, E. E., Kara, E. M., Yılmaz, M. A., Zengin, G. ve Boğa, M. (2019). Comprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn. Journal of Food Biochemistry, 43(7), 1-10.en_US
dc.identifier.doi10.1111/jfbc.12928
dc.identifier.endpage10en_US
dc.identifier.issn0145-8884
dc.identifier.issue7en_US
dc.identifier.pmid31353714
dc.identifier.scopus2-s2.0-85066908415
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1111/jfbc.12928
dc.identifier.urihttps://hdl.handle.net/11468/12938
dc.identifier.volume43en_US
dc.identifier.wosWOS:000474303400045
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.institutionauthorBoğa, Mehmet
dc.language.isoenen_US
dc.publisherBlackwell Publishing Ltd.en_US
dc.relation.ispartofJournal of Food Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectAllium macrochaetumen_US
dc.subjectAnticholinesteraseen_US
dc.subjectAntimicrobialen_US
dc.subjectAntioxidanten_US
dc.subjectEssential oilen_US
dc.subjectFatty aciden_US
dc.titleComprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn.en_US
dc.titleComprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn.
dc.typeArticleen_US

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