CT diagnosis of intrasplenic metastasis from ovarian carcinoma

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dc.contributor.authorSenturk, Senem
dc.contributor.authorKarcaaltincaba, Musturay
dc.contributor.authorAkata, Deniz
dc.date.accessioned2024-04-24T16:11:21Z
dc.date.available2024-04-24T16:11:21Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntrasplenic metastases from ovarian carcinoma cannot be always demonstrated intraoperatively. CT is the most important imaging modality of choice for staging and follow-up ovarian cancer; in this study we searched CT appearances of intrasplenic metastases from ovarian carcinoma. We retrospectively reviewed imaging histories of the patients with ovarian cancer from the radiology information system, and found 12 patients with intrasplenic metastasis. All patients underwent abdominal CT with 16-MDCT. We searched number, density and maximum diameters of splenic metastasis. The growing rate of three lesions, which were followed up by CT, was calculated. Serum cancer antigen (CA) 125 levels were noted. We also evaluated clinical history and pathology reports of all patients. Splenic metastases, solitary or multiple, were detected most frequently during the follow-up (1-14 years after initial diagnosis) and most were associated with other sites of recurrence. The diameters of lesions ranged from 4 to 85 mm. All lesions appeared hypodense except for one lesion with dense calcification. Densities of lesions ranged from 12 to 208 Hounsfield units (mean, 49 +/- 51 HU). Most lesions appeared as solid well-defined nodules; however some lesions had lobulated and irregular contours with an infiltrative pattern. The growing rates of three lesions were 0.72 mm/month, 1.75 mm/month and 2.70 mm/month. Eight patients had elevated serum CA 125 levels (40-1256 U/mL). We concluded that CT can demonstrate intraparenchymal and infiltrative splenic metastasis in patients with ovarian cancer even in the absence of increased CA 125 levels. (C) 2011 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejrad.2011.02.058
dc.identifier.endpage1099en_US
dc.identifier.issn0720-048X
dc.identifier.issue6en_US
dc.identifier.pmid21439748
dc.identifier.scopus2-s2.0-84860780065
dc.identifier.scopusqualityQ1
dc.identifier.startpage1094en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejrad.2011.02.058
dc.identifier.urihttps://hdl.handle.net/11468/15364
dc.identifier.volume81en_US
dc.identifier.wosWOS:000303813100003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofEuropean Journal of Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComputed Tomographyen_US
dc.subjectNeoplasm Metastasisen_US
dc.subjectOvarian Neoplasmsen_US
dc.subjectSplenic Neoplasmsen_US
dc.titleCT diagnosis of intrasplenic metastasis from ovarian carcinomaen_US
dc.titleCT diagnosis of intrasplenic metastasis from ovarian carcinoma
dc.typeArticleen_US

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