Probable preventive effects of placenta from oxidative stress; Evaluation of total antioxidant status, total oxidant status and oxidative stress index in fetal cord blood during the delivery

dc.contributor.authorCamkurt, Mehmet Akif
dc.contributor.authorFindikh, Ebru
dc.contributor.authorTolun, Fatma Inanc
dc.contributor.authorBakacak, Murat
dc.contributor.authorBal, Nilay Gul
dc.contributor.authorSakalh, Hilal
dc.contributor.authorGunes, Mehmet
dc.date.accessioned2024-04-24T16:18:18Z
dc.date.available2024-04-24T16:18:18Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractDepression in pregnancy may have negative effects on birth outcomes. It may also effect the intrauterine environment of the fetus. The umbilical cord is the conduit between the fetus and placenta, and functions in the transport between fetus and mother. Investigating biochemical parameters in fetal cord blood (FCB) during delivery may be helpful to understanding to what the fetus is exposed to, at least in the last trimester. In this study, we aimed to investigate total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) in the FCB of depressed mothers and healthy controls during delivery. Our study included 33 depressed mothers and 37 healthy controls. TAS, TOS, and OSI were measured according to Erel's method. We found that TAS, TOS, and OSI levels were similar in patients and healthy controls; however, the birth weights of depressed patients were significantly lower than those of healthy controls. Our results suggest that the placental barrier may prevent from oxidative stress. Future studies should include blood samples collected simultaneously from mothers during delivery. (C) 2016 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.psychres.2016.03.054
dc.identifier.endpage225en_US
dc.identifier.issn0165-1781
dc.identifier.pmid27124206
dc.identifier.scopus2-s2.0-84964322483
dc.identifier.scopusqualityQ1
dc.identifier.startpage222en_US
dc.identifier.urihttps://doi.org/10.1016/j.psychres.2016.03.054
dc.identifier.urihttps://hdl.handle.net/11468/15978
dc.identifier.volume240en_US
dc.identifier.wosWOS:000378359500034
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofPsychiatry Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleProbable preventive effects of placenta from oxidative stress; Evaluation of total antioxidant status, total oxidant status and oxidative stress index in fetal cord blood during the deliveryen_US
dc.titleProbable preventive effects of placenta from oxidative stress; Evaluation of total antioxidant status, total oxidant status and oxidative stress index in fetal cord blood during the delivery
dc.typeArticleen_US

Dosyalar