Parental Decisions Regarding a Prenatally Detected Fetal Chromosomal Abnormality and the Impact of Genetic Counseling: An Analysis of 38 Cases with Aneuploidy in Southeast Turkey

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dc.contributor.authorBalkan, Mahmut
dc.contributor.authorKalkanli, Sevgi
dc.contributor.authorAkbas, Halit
dc.contributor.authorYalinkaya, Ahmet
dc.contributor.authorAlp, M. Nail
dc.contributor.authorBudak, Turgay
dc.date.accessioned2024-04-24T16:02:15Z
dc.date.available2024-04-24T16:02:15Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis study investigated parental decision-making to terminate or continue a pregnancy after prenatal diagnosis of a chromosomal abnormality among a sample of patients in Southeast Turkey. Between 2004 and 2007, 1068 amniocentesis tests were performed in the Medical Biology and Genetic Department Laboratory at Dicle University. Aneuploidy was found in 38 cases (3.56%). Genetic counseling was provided for the couples that received abnormal results, and they were later interviewed and asked if they had continued or interrupted the pregnancy after the diagnosis. When confronted with autosomal aneuploidy in which a severe prognosis was expected, 85% of cases decided to terminate the pregnancy. When confronted with sex chromosome aneuploidy with a low risk of an abnormal clinical phenotype 60% of cases decided to continue the pregnancy. Among the diagnoses with aneuploidy, pregnancy was continued in 21.1% of cases due to religious beliefs regardless of whether there was a low or severe risk of an abnormal clinical phenotype. These findings indicate that both severity of abnormality and religiosity play an important role in genetic counseling patients' decision-making processes and outcomes in Turkey. In addition, the findings suggest the need for legislation that reduces the differences in approaches between the physicians and institutions regarding parental decision-making to terminate or continue a pregnancy in our country.en_US
dc.identifier.doi10.1007/s10897-009-9275-3
dc.identifier.endpage246en_US
dc.identifier.issn1059-7700
dc.identifier.issue3en_US
dc.identifier.pmid20119701
dc.identifier.scopus2-s2.0-77953325109
dc.identifier.scopusqualityQ3
dc.identifier.startpage241en_US
dc.identifier.urihttps://doi.org/10.1007/s10897-009-9275-3
dc.identifier.urihttps://hdl.handle.net/11468/14707
dc.identifier.volume19en_US
dc.identifier.wosWOS:000277958500005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Genetic Counseling
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPrenatal Diagnosisen_US
dc.subjectGenetic Counselingen_US
dc.subjectAutosomal Aneuploidyen_US
dc.subjectSex Chromosome Aneuploidyen_US
dc.subjectPregnancy Terminationen_US
dc.subjectReligiousen_US
dc.subjectTurkeyen_US
dc.titleParental Decisions Regarding a Prenatally Detected Fetal Chromosomal Abnormality and the Impact of Genetic Counseling: An Analysis of 38 Cases with Aneuploidy in Southeast Turkeyen_US
dc.titleParental Decisions Regarding a Prenatally Detected Fetal Chromosomal Abnormality and the Impact of Genetic Counseling: An Analysis of 38 Cases with Aneuploidy in Southeast Turkey
dc.typeArticleen_US

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