Dependence of clinical outcomes on time of hospital admission in patients with ST-segment elevation myocardial infarction

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dc.authorid0000-0003-2243-6190en_US
dc.authorid0000-0002-2145-9406en_US
dc.contributor.authorÖzbek, Mehmet
dc.contributor.authorIldirimli, Kamran
dc.contributor.authorArık, Baran
dc.contributor.authorAktan, Adem
dc.contributor.authorCoşkun, Mehmet Sait
dc.contributor.authorEvsen, Ali
dc.contributor.authorGüzel, Tuncay
dc.contributor.authorAcet, Halit
dc.contributor.authorDemira, Muhammed
dc.date.accessioned2023-09-28T12:45:33Z
dc.date.available2023-09-28T12:45:33Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractBACKGROUND: There are conflicting results in studies investigating the effects of percutaneous coronary intervention (PCI) on the prognosis of patients with ST-segment elevation myocardial infarction (STEMI) during or outside of usual hospital working hours. While some researchers have reported higher mortality rates in STEMI patients admitted outside of working hours, others did not find a statistically significant difference. OBJECTIVES: Investigate the short-term endpoints and long-term outcomes of STEMI patients by time of admission. DESIGN: Retrospective SETTING: Tertiary percutaneous coronary intervention center. PATIENTS AND METHODS: Patients were grouped by admission, which consisted of four intervals: 06:00 to <12:00, 12:00 to <18:00, 18:00 to <24:00, and 24:00 to <06:00. We analyzed demographic, clinical and mortality by admission time interval and mortality by multivariate analyses, including the time intervals. MAIN OUTCOME MEASURES: Clinical data and mortality SAMPLE SIZE: 735 patients; median (IQR) age 62 (22) years; 215 (29.3%) women. RESULTS: Patients admitted at night were 1.37 times more likely to experience pulmonary edema than patients whose symptoms started in the daytime (P=.012); 32.9% of the patients whose symptoms started at night presented with Killip class II-IV, while during the daytime, 21.4% presented with Killip class II-IV (P=.001). Among the patients, the most common was inferior STEMI (38.6%). However, no-reflow was significantly higher during the daytime compared to the nighttime (P=.12). The risk of the cardiac arrest on admission was 1.2 times higher in patients admitted at night (P=.034). Neither time interval of admission nor several other variables had an effect on clinical outcome or mortality. CONCLUSIONS: While patients admitted at night presented with pulmonary edema and cardiogenic shock more frequently, no reflow was observed during the day after the procedure. Although patients admitted at night with STEMI presented with worse clinical conditions, similar results were observed between the groups in clinical outcomes. LIMITATIONS: More “real world” results might have been obtained if the study had replicated more typical referral conditions for PCI. CONFLICT OF INTEREST: None.en_US
dc.identifier.citationÖzbek, M., Ildirimli, K., Arık, B., Aktan, A., Coşkun, M. S., Evsen, A. ve diğerleri. (2023). Dependence of clinical outcomes on time of hospital admission in patients with ST-segment elevation myocardial infarction. Annals of Saudi Medicine, 43(1), 25-34.en_US
dc.identifier.doi10.5144/0256-4947.2023.25
dc.identifier.endpage34en_US
dc.identifier.issn0256-4947
dc.identifier.issue1en_US
dc.identifier.pmid36739499
dc.identifier.scopus2-s2.0-85147390159
dc.identifier.scopusqualityQ2
dc.identifier.startpage25en_US
dc.identifier.urihttps://www.annsaudimed.net/doi/10.5144/0256-4947.2023.25
dc.identifier.urihttps://hdl.handle.net/11468/12622
dc.identifier.volume43en_US
dc.identifier.wosWOS:000947871800004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzbek, Mehmet
dc.institutionauthorIldirimli, Kamran
dc.institutionauthorArık, Baran
dc.institutionauthorAktan, Adem
dc.institutionauthorCoşkun, Mehmet Sait
dc.institutionauthorEvsen, Ali
dc.institutionauthorGüzel, Tuncay
dc.institutionauthorAcet, Halit
dc.institutionauthorDemira, Muhammed
dc.language.isoenen_US
dc.publisherKing Faisal Specialist Hospital and Research Centreen_US
dc.relation.ispartofAnnals of Saudi Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectST-segmenten_US
dc.subjectMyocardial infarctionen_US
dc.titleDependence of clinical outcomes on time of hospital admission in patients with ST-segment elevation myocardial infarctionen_US
dc.titleDependence of clinical outcomes on time of hospital admission in patients with ST-segment elevation myocardial infarction
dc.typeArticleen_US

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