Efficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in children

Basit Öğe Kaydı
dc.contributor.authorKeklikci, Ugur
dc.contributor.authorSoker, Sevda I.
dc.contributor.authorSakalar, Yildirim B.
dc.contributor.authorUnlu, Kaan
dc.contributor.authorOzekinci, Selver
dc.contributor.authorTunik, Selcuk
dc.date.accessioned2024-04-24T16:02:05Z
dc.date.available2024-04-24T16:02:05Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractTo evaluate the efficacy of topical cyclosporin A 0.05% in managing the symptoms of severe vernal keratoconjunctivitis (VKC). Fifty-four children with severe VKC were included in this study. All 54 patients were treated with topical cyclosporin A (CsA) 0.05% for 3 months. Ocular signs and symptoms were scored in all patients at entry and after 3 months. Conjunctival impression cytology specimens were examined on the day of enrollment and at the end of the treatment period. The mean scores for severity of signs and symptoms significantly decreased after 3 months compared with those at entry (P < 0.001). The density of inflammatory cells in the conjunctival impression cytology specimens decreased significantly. No side effects of the treatment with CsA 0.05% eyedrops were observed. Topical CsA 0.05% eyedrops were found to be safe and effective in the treatment of patients with VKC. Consistent with these results, topical CsA may efficiently reduce conjunctival inflammation in severe VKC.en_US
dc.identifier.doi10.1007/s10384-008-0577-z
dc.identifier.endpage362en_US
dc.identifier.issn0021-5155
dc.identifier.issue5en_US
dc.identifier.pmid18991035
dc.identifier.scopus2-s2.0-55949127666
dc.identifier.scopusqualityQ1
dc.identifier.startpage357en_US
dc.identifier.urihttps://doi.org/10.1007/s10384-008-0577-z
dc.identifier.urihttps://hdl.handle.net/11468/14619
dc.identifier.volume52en_US
dc.identifier.wosWOS:000260795900002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Tokyoen_US
dc.relation.ispartofJapanese Journal of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCyclosporinen_US
dc.subjectImpression Cytologyen_US
dc.subjectVernal Keratoconjunctivitisen_US
dc.titleEfficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in childrenen_US
dc.titleEfficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in children
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu