Does the Histopathologic Pattern of the Ureteropelvic Junction Affect the Outcome of Pyeloplasty?

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dc.contributor.authorIssi, Oktay
dc.contributor.authorDeliktas, Hasan
dc.contributor.authorGedik, Abdullah
dc.contributor.authorOzekinci, Selver
dc.contributor.authorBircan, Mehmet Kamuran
dc.contributor.authorSahin, Hayrettin
dc.date.accessioned2024-04-24T17:33:30Z
dc.date.available2024-04-24T17:33:30Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: To investigate the effects of the histopathologic pattern of obstructed ureteropelvic junction (UPJ) specimens, including collagen type 3, elastin, fibrosis and Cajal cells, on the outcome of pyeloplasty. Materials and Methods: Histopathological specimens obtained following Anderson-Hynes pycloplasty from 52 patients with intrinsic ureteropelvic junction obstruction (UPJO) between January 2005 and January 2008 were evaluated histopathologically. Patients with extrinsic or secondary UPJO were excluded. Preoperative and postoperative radiographic evaluations were performed either via diuretic renography or intravenous pyelography, or both. Six months post-surgery the patients were divided into 2 groups, as successful surgery (group 1) and unsuccessful surgery (group 2). Histopathological findings (collagen type 3, elastin, fibrosis and Cajal cells) in each group were statistically compared. Results: The study included 52 patients (21 female and 31 male). Mean age of the entire study population was 39.42 +/- 14.5 years, versus 39.63 +/- 14.9 years in group 1 (n = 47) and 37.4 +/- 10.0 years in group 2 (n = 5). Median follow-up was 18 months. There weren't any significant differences in collagen type 3, elastin, fibrosis, or Cajal cells between the 2 groups (P > .05). Conclusion: The histopathologic pattern of UPJ was not a factor associated with the success of pyeloplasty. Based on the present findings, we conclude that surgical technique is more important than the histopathologic pattern of UPJ for the successful treatment of UPJO.en_US
dc.identifier.endpage2031en_US
dc.identifier.issn1735-1308
dc.identifier.issn1735-546X
dc.identifier.issue1en_US
dc.identifier.pmid25703913
dc.identifier.scopus2-s2.0-84929832519
dc.identifier.scopusqualityQ3
dc.identifier.startpage2028en_US
dc.identifier.urihttps://hdl.handle.net/11468/20722
dc.identifier.volume12en_US
dc.identifier.wosWOS:000351258300008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherUrol & Nephrol Res Ctr-Unrcen_US
dc.relation.ispartofUrology Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKidney Pelvisen_US
dc.subjectSurgeryen_US
dc.subjectTreatment Outcomeen_US
dc.subjectUreteral Obstructionen_US
dc.subjectFollow-Up Studiesen_US
dc.subjectPhysiopathologyen_US
dc.titleDoes the Histopathologic Pattern of the Ureteropelvic Junction Affect the Outcome of Pyeloplasty?en_US
dc.titleDoes the Histopathologic Pattern of the Ureteropelvic Junction Affect the Outcome of Pyeloplasty?
dc.typeArticleen_US

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