QTc prolongation and torsade de pointes ventricular tachycardia in a small dose voriconazole therapy

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dc.contributor.authorElbey, M. A.
dc.contributor.authorCil, H.
dc.contributor.authorOnturk, E.
dc.contributor.authorIslamoglu, Y.
dc.date.accessioned2024-04-24T17:37:53Z
dc.date.available2024-04-24T17:37:53Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractTorsade de pointes (TdP) is a life-threatening arrhythmia that can result from long QT syndrome. Drug-induced QT prolongation is a potentially dangerous adverse effect of some drug combinations. A 34-year-old woman with history of nephrotic syndrome and rheumatic mitral valve disease was admitted to our Hospital because of high fever. The patient continued to be febrile until antifungal treatment was switched to voriconazole. The electrocardiogram demonstrated sinus tachycardia and a prolonged QTc interval of 580 ms. Patient was resuscitated with electrical cardioversion and had an emergent temporary pacemaker placed. We recommend careful monitoring for QTc prolongation and arrhythmia in patients who are receiving voriconazole, particularly those who have significant electrolyte disturbances.en_US
dc.identifier.endpage102en_US
dc.identifier.issn1128-3602
dc.identifier.issue1en_US
dc.identifier.pmid22338554
dc.identifier.scopus2-s2.0-84859820436
dc.identifier.scopusqualityQ2
dc.identifier.startpage100en_US
dc.identifier.urihttps://hdl.handle.net/11468/21232
dc.identifier.volume16en_US
dc.identifier.wosWOS:000300114800013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVoriconazoleen_US
dc.subjectQtc Prolongationen_US
dc.subjectTorsades De Pointesen_US
dc.titleQTc prolongation and torsade de pointes ventricular tachycardia in a small dose voriconazole therapyen_US
dc.titleQTc prolongation and torsade de pointes ventricular tachycardia in a small dose voriconazole therapy
dc.typeArticleen_US

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