Management of non-traumatic acute limb ischemia and predictors of outcome in 270 thrombembolectomy cases

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dc.contributor.authorTopal, A. Ender
dc.contributor.authorEren, M. Nesimi
dc.contributor.authorCelik, Y.
dc.date.accessioned2024-04-24T17:37:38Z
dc.date.available2024-04-24T17:37:38Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim. Acute limb ischemia (ALI) is one of the most potentially devastating but treatable diseases, resulting from a sudden obstruction in the arterial flow. The aim of this study was to examine the outcome of thromboembolectomy, and to determine the risk factors associated with limb loss and mortality in ALI. Methods. A retrospective chart review of 270 patients on whom thromboembolectomy was performed between September 2002 and December 2009 due to ALI. Of these, 146 (54.1%) were men and mean age was 64.3. Results. Etiology was embolic in 63.3% of cases. Late thromboembolectomy after 72 hours was performed in 57.8% of patients. On admission 38.9% of patients had grade IIb ischemia; grade III ischemia was present in 9.6% of patients. Failure of first thromboembolectomy developed in 21.1% of patients and bypass surgery was performed on 25.2% of patients. Amputation and mortality rates were 7.4% and 8.5% respectively. Binary logistic regression analysis revealed that risk factors of limb loss were thromboembolectomy failure, high ischemic stage, high level of plasma creatinine kinase and compartment syndrome on admission and predictors of mortality were congestive heart failure, ischemic heart disease, reperfusion injury and longer ischemic time. Conclusion. In ALI, thromboembolectomy is highly protective against amputation, as well as mortality, even in delayed cases with more than one week in the clinical absence of tissue necrosis. At least, it provides partial limb salvage. In addition, patients must be given a chance for limb salvage in the case of stage 3 ischemia, too. [Int Angiol 2011;30:172-80]en_US
dc.identifier.endpage180en_US
dc.identifier.issn0392-9590
dc.identifier.issn1827-1839
dc.identifier.issue2en_US
dc.identifier.pmid21427655en_US
dc.identifier.scopus2-s2.0-79955786106en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage172en_US
dc.identifier.urihttps://hdl.handle.net/11468/21083
dc.identifier.volume30en_US
dc.identifier.wosWOS:000290743200011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofInternational Angiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Limb Ischemiaen_US
dc.subjectThromboembolismen_US
dc.subjectRisk Factorsen_US
dc.titleManagement of non-traumatic acute limb ischemia and predictors of outcome in 270 thrombembolectomy casesen_US
dc.typeArticleen_US

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