Chemical and Biological Perspectives of Monoterpene Indole Alkaloids From Rauwolfia species

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dc.authorid0000-0002-8325-8116en_US
dc.authorid0000-0002-3909-0694en_US
dc.authorid0000-0003-4163-9962en_US
dc.contributor.authorBoğa, Mehmet
dc.contributor.authorBingül, Murat
dc.contributor.authorÖzkan, Esra Eroğlu
dc.contributor.authorŞahin, Hasan
dc.date.accessioned2024-02-23T13:19:06Z
dc.date.available2024-02-23T13:19:06Z
dc.date.issued2018en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bililmleri Bölümüen_US
dc.description.abstractThe biosynthesis of monoterpene indole alkaloids (MIAs) starts with a geraniol for the terpenoid portion. Secologanin, a secoiridoid glycoside, is derived from 10-hydroxygeraniol, produced in the presence of geraniol 10-hydroxylase. The indole portion of MIAs contain tryptamine, produced by the decarboxylation of tryptophan. Conjugation of secologanin with tryptamine is achieved with strictosidine synthase to produce strictosidine. Over 2500 known MIAs found in many plants from several families, such as Apocynaceae, Loganiaceae, Rubiaceae, and Nyssaceae, are produced by modification of strictosidine. A number of pharmacologically active compounds, namely, reserpine, ajmalicine, ajmaline, serpentine, and yohimbine, isolated from different Rauwolfia species, are examples of MIAsen_US
dc.identifier.citationBoğa, M., Bingül, M., Özkan, E.E. ve Şahin, H. (2018). Chemical and Biological Perspectives of Monoterpene Indole Alkaloids From Rauwolfia species. A. Rahman (Ed.). Studies in Natural Products Chemistry içinde. (pp. 251-299). Cambridge: Elsevier.en_US
dc.identifier.endpage299en_US
dc.identifier.isbn978-0-444-64183-0
dc.identifier.issn1572-5995
dc.identifier.scopusScopusIdYok
dc.identifier.scopusqualityQ3
dc.identifier.startpage251en_US
dc.identifier.urihttps://hdl.handle.net/11468/13380
dc.identifier.volume61en_US
dc.identifier.wosWOS:000488069200008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorBoğa, Mehmet
dc.institutionauthorBingül, Murat
dc.institutionauthorŞahin, Hasan
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofStudies in Natural Products Chemistry
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMonoterpene Indole Alkaloids From Rauwolfia speciesen_US
dc.titleChemical and Biological Perspectives of Monoterpene Indole Alkaloids From Rauwolfia speciesen_US
dc.titleChemical and Biological Perspectives of Monoterpene Indole Alkaloids From Rauwolfia species
dc.typeBook Chapteren_US

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