Evaluation of retrobulbar blood flow by color doppler ultrasonography after intravitreal ranibizumab injection in patients with neovascular age-related macular degeneration

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dc.contributor.authorSakalar, Yıldırım Bayezit
dc.contributor.authorŞentürk, Senem
dc.contributor.authorYıldırım, Mine
dc.contributor.authorKeklikçi, Uğur
dc.contributor.authorAlakuş, Mehmet Fuat
dc.contributor.authorÜnlü, Kaan
dc.date.accessioned2024-04-24T15:59:26Z
dc.date.available2024-04-24T15:59:26Z
dc.date.issued2013
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractPurpose. This study aimed to evaluate the changes in retrobulbar blood flow by using color Doppler sonography in patients who had undergone intravitreal ranibizumab injection for neovascular age-related macular degeneration (AMD). Methods. The study comprised 37 AMD patients who had undergone intravitreal 0.5 mg ranibizumab injection. The ophthalmic artery, central retinal artery, and short lateral posterior ciliary artery of both eyes of patients were evaluated by color Doppler sonography. Peak systolic velocity, end-diastolic velocity, and resistance index were calculated before injection, and after injection on day 7 and day 30. The pre- and postinjection values were compared using Wilcoxon signed rank test. Results. In a comparison with the preinjection values of peak systolic velocity, end-diastolic velocity, and resistance index, the postinjection values at both day 7 and day 30 showed no statistically significant difference in ophthalmic artery, lateral posterior ciliary artery, and central retinal artery (p > 0.05). Similarly, for the same parameters, pre- and postinjection values in the uninjected fellow eye showed no statistically significant difference (P > 0.05). Conclusions. Intravitreal ranibizumab injection for neovascular AMD does not cause a significant change in the retrobulbar blood flow in either the injected eye or the fellow eye.en_US
dc.identifier.citationSakalar, Y. B., Şentürk, S., Yıldırım, M., Keklikçi, U., Alakuş, M. F. ve Ünlü, K. (2013). Evaluation of retrobulbar blood flow by color doppler ultrasonography after intravitreal ranibizumab injection in patients with neovascular age-related macular degeneration. Journal of Clinical Ultrasound, 41(1), 32-37.
dc.identifier.doi10.1002/jcu.21989
dc.identifier.endpage37en_US
dc.identifier.issn0091-2751
dc.identifier.issue1en_US
dc.identifier.pmid23055187
dc.identifier.scopus2-s2.0-84871013814
dc.identifier.scopusqualityQ3
dc.identifier.startpage32en_US
dc.identifier.urihttps://doi.org/10.1002/jcu.21989
dc.identifier.urihttps://hdl.handle.net/11468/14064
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/jcu.21989
dc.identifier.volume41en_US
dc.identifier.wosWOS:000312536600005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSakalar, Yıldırım Bayezit
dc.institutionauthorYıldırım, Mine
dc.institutionauthorKeklikçi, Uğur
dc.institutionauthorAlakuş, Mehmet Fuat
dc.institutionauthorÜnlü, Kaan
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofJournal of Clinical Ultrasound
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColor doppler ultrasonographyen_US
dc.subjectRetrobulbar blood flowen_US
dc.subjectAge-related macular degenerationen_US
dc.subjectRanibizumaben_US
dc.subjectEyeen_US
dc.titleEvaluation of retrobulbar blood flow by color doppler ultrasonography after intravitreal ranibizumab injection in patients with neovascular age-related macular degenerationen_US
dc.titleEvaluation of retrobulbar blood flow by color doppler ultrasonography after intravitreal ranibizumab injection in patients with neovascular age-related macular degeneration
dc.typeArticleen_US

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