Analysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesions

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dc.contributor.authorBarut, Mert Ulaş
dc.contributor.authorKale, Ahmet
dc.contributor.authorKuyumcuoğlu, Umur
dc.contributor.authorBozkurt, Murat
dc.contributor.authorAğaçayak, Elif
dc.contributor.authorÖzekinci, Server
dc.contributor.authorGül, Talip
dc.date.accessioned2024-04-24T17:15:07Z
dc.date.available2024-04-24T17:15:07Z
dc.date.issued2015
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractBackground: This study aimed to examine the positive and negative predictive value in the diagnosis of premalignant and malignant lesions of cervical colposcopy, the sensitivity and specificity of smear, and to evaluate the correlation with histopathology of abnormal cytology and colposcopy. Material/Methods: The criteria for inclusion of patients with unhealthy cervix in the study were: Erosion, Chronic cervicitis, and Healed lacerations, Hypertrophied cervix, bleeding on touch, suspicious growth/ulcer/polyp on the cervix, and abnormal discharges from the cervix. Women with frank carcinoma cervix, pregnant females, patients with bleeding per vaginum at the time of examination, and those who had used vaginal medications, vaginal contraceptives or douches in the last 48 h of examination were excluded from the study. Demographic analysis was performed for 450 patients who were admitted to the clinic. Sensitivity, specificity, positive predictive value and negative predictive values of patients to identify cervical pathologies of smear and colposcopy were histopathologically calculated. The statistical software package SPSS 15.0 (SPSS Inc., Chicago, IL, USA) and Spearman's and Chi-Square tests were used for statistical analysis. Results: Sensitivity, specificity, PPD and NDP of smear were 0.57%, 0.76%, 0.26%, 0.92% respectively. Sensitivity, specificity, PPD and NDP of colposcopy were 0.92%, 0.67%, 0.52%, 0.96% respectively. A statistically significant correlation was found between abnormal cytology and histopathology, and abnormal colposcopy finding and histopathology. Conclusions: Women with clinical diagnosis of unhealthy cervix should be evaluated by cytology to detect any premalignant or malignant lesions. It was concluded that Pap smear, colposcopy and histopathology should be collectively evaluated to evaluate cervical findings in low socio-economic regions.en_US
dc.identifier.citationBarut, M. U., Kale, A., Kuyumcuoğlu, U., Bozkurt, M., Ağaçayak, E., Özekinci, S. ve diğerleri. (2015). Analysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesions. Medical Science Monitor, 21, 3860-3867.
dc.identifier.doi10.12659/MSM.895227
dc.identifier.endpage3867en_US
dc.identifier.issn1643-3750
dc.identifier.pmid26655816
dc.identifier.scopus2-s2.0-84949777194
dc.identifier.scopusqualityQ1
dc.identifier.startpage3860en_US
dc.identifier.urihttps://doi.org/10.12659/MSM.895227
dc.identifier.urihttps://hdl.handle.net/11468/18340
dc.identifier.volume21en_US
dc.identifier.wosWOS:000367354300002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt Scientific Literature, Incen_US
dc.relation.ispartofMedical Science Monitor
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColposcopyen_US
dc.subjectCytological techniquesen_US
dc.subjectUterine cervical neoplasmsen_US
dc.titleAnalysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesionsen_US
dc.titleAnalysis of sensitivity, specificity, and positive and negative predictive values of smear and colposcopy in diagnosis of premalignant and malignant cervical lesions
dc.typeArticleen_US

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