Botulinum toxin A in the treatment of spasticity - An open label study

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dc.contributor.authorTurhanoglu, AD
dc.contributor.authorKarabulut, Z
dc.contributor.authorBayram, H
dc.contributor.authorTurhanoglu, S
dc.contributor.authorErdogan, F
dc.contributor.authorApak, I
dc.contributor.authorYayla, V
dc.date.accessioned2024-04-24T17:20:42Z
dc.date.available2024-04-24T17:20:42Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: To assess the efficacy of botulinum toxin type A in spasticity in upper-motor neuron syndromes. Methods: Twenty-three patients with spasticity resulted from stroke-related hemiplegia, transverse myelitis and multiple sclerosis took part in the study. Following the history and physical examinations of the patients, injections of botulinum toxin-A were applied. The dose ranged from 80 to 400 mouse unit (MU) depending on the size of the muscle injected. In all patients, spasticity, spasms and pain were measured using the Ashworth Scale, Spasm Frequency Score, and Visual Analogue Scale prior to the therapy, at the 1st week, 1st month and 3rd month of the therapy. Results: In all patients, botulinum toxin type A led to a significant decrease in spasticity, spasms and pain after the 1st week, 1st and 3rd months of the treatment when compared to the baseline values (p < 0.001). No significant side effects or complications were observed. Conclusion: Our results have demonstrated that botulinum toxin type A is effective in the management of patients with spasticity due to stroke-related hemiplegia, transverse myelitis and multiple sclerosis, without major adverse effects.en_US
dc.identifier.doi10.3233/BMR-2002-162-301
dc.identifier.endpage56en_US
dc.identifier.issn1053-8127
dc.identifier.issue2-3en_US
dc.identifier.pmid22387399
dc.identifier.scopus2-s2.0-0036985847
dc.identifier.scopusqualityQ2
dc.identifier.startpage51en_US
dc.identifier.urihttps://doi.org/10.3233/BMR-2002-162-301
dc.identifier.urihttps://hdl.handle.net/11468/19204
dc.identifier.volume16en_US
dc.identifier.wosWOS:000182760100001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherIos Pressen_US
dc.relation.ispartofJournal of Back and Musculoskeletal Rehabilitation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleBotulinum toxin A in the treatment of spasticity - An open label studyen_US
dc.titleBotulinum toxin A in the treatment of spasticity - An open label study
dc.typeArticleen_US

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