The effects of long-term exposure to extremely low-frequency magnetic fields on bone formation in ovariectomized rats

dc.contributor.authorÇelik, Mustafa Salih
dc.contributor.authorGür, Ali
dc.contributor.authorAkdağ, Zülküf
dc.contributor.authorAkpolat, Veysi
dc.contributor.authorGüven, Kemal
dc.contributor.authorÇelik, Yusuf
dc.contributor.authorSaraç, Aysegül Jale
dc.contributor.authorOtçu, Selçuk
dc.contributor.orcid0000-0002-2435-7800
dc.contributor.orcid0000-0002-0181-3746
dc.contributor.orcid0000-0003-2849-4033
dc.date.accessioned2024-04-24T15:59:20Z
dc.date.available2024-04-24T15:59:20Z
dc.date.issued2012
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalıen_US
dc.description.abstractThe effects of long-term extremely low-frequency magnetic field (ELF-MF) exposure on bone formation and biochemical markers were investigated in ovariectomized rats. Sixty mature female SpragueDawley rats were randomly divided into four different groups (n?=?15): (i) unexposed control (CTL); (ii) ovariectomized only (OVX); (iii) non-ovariectomized, exposed (SHAM?+?ELF-MF); and (iv) ovariectomized, exposed (OVX?+?ELF-MF). The third and fourth groups were exposed to 1.5?mT ELF-MF for 4?h a day for 6 months. Bone mineral density (BMD) was determined using dual energy X-ray absorption (DEXA) measurements. The formation and resorption of bone were evaluated using bone-specific alkaline phosphatase (BAP), osteocalcin, osteoprotogerin, and N-telopeptide. After 6 months of ELF-MF therapy, BMD values were significantly lower in the OVX group and higher in the OVX?+?ELF-MF and SHAM?+?ELF-MF groups than they were before therapy (P?en_US
dc.description.sponsorshipResearch Foundation of Dicle University [DUAPK-02-TF-02]en_US
dc.description.sponsorshipGrant sponsor: Research Foundation of Dicle University; Grant number: DUAPK-02-TF-02.en_US
dc.identifier.citationÇelik, M. S., Gür, A., Akdağ, Z., Akpolat, V., Güven, K., Çelik, Y. ve diğerleri. (2012). The effects of long-term exposure to extremely low-frequency magnetic fields on bone formation in ovariectomized rats. Bioelectromagnetics, 33(7), 543-549.
dc.identifier.doi10.1002/bem.21725
dc.identifier.endpage549en_US
dc.identifier.issn0197-8462
dc.identifier.issn1521-186X
dc.identifier.issue7en_US
dc.identifier.pmid22487936
dc.identifier.scopus2-s2.0-84866156784
dc.identifier.scopusqualityQ2
dc.identifier.startpage543en_US
dc.identifier.urihttps://doi.org/10.1002/bem.21725
dc.identifier.urihttps://hdl.handle.net/11468/13988
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.21725
dc.identifier.volume33en_US
dc.identifier.wosWOS:000308632100002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇelik, Mustafa Salih
dc.institutionauthorGür, Ali
dc.institutionauthorAkdağ, Zülküf
dc.institutionauthorAkpolat, Veysi
dc.institutionauthorGüven, Kemal
dc.institutionauthorÇelik, Yusuf
dc.institutionauthorSaraç, Aysegül Jale
dc.institutionauthorOtçu, Selçuk
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofBioelectromagnetics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExtremely Low-Frequency Magnetic Fielden_US
dc.subjectOsteoporosisen_US
dc.subjectBone mineral densityen_US
dc.subjectOsteocalcinen_US
dc.subjectOsteoprotogerinen_US
dc.subjectN-telopeptideen_US
dc.subjectBone-specific alkaline phosphataseen_US
dc.titleThe effects of long-term exposure to extremely low-frequency magnetic fields on bone formation in ovariectomized ratsen_US
dc.titleThe effects of long-term exposure to extremely low-frequency magnetic fields on bone formation in ovariectomized rats
dc.typeArticleen_US

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