Discrimination ability of ASDAS estimating disease activity status in patients with ankylosing spondylitis

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dc.contributor.authorNas, Kemal
dc.contributor.authorYildirim, Kadir
dc.contributor.authorCevik, Remzi
dc.contributor.authorKaratay, Saliha
dc.contributor.authorErdal, Akin
dc.contributor.authorBaysal, Ozlem
dc.contributor.authorAltay, Zuhal
dc.date.accessioned2024-04-24T17:11:40Z
dc.date.available2024-04-24T17:11:40Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: To investigate discrimination ability of the Assessment of Spondyloarthritis International Society (ASAS) endorsed disease activity score (ASDAS) versions evaluating low and high disease activity in an unselected group of patients with ankylosing spondylitis (AS). Methods: Patients consecutively included into the joint database of five university hospitals were analyzed for low or high disease activity according to different criteria. Standardized mean differences (SMD) for two ASDAS versions were evaluated. Results: The ASDAS versions (back pain, morning stiffness, patient global pain, pain/swelling of peripheral joints, plus either erythrocyte sedimentation rate or C-reactive protein) discriminated high and low disease activity in subgroups according to Bath Ankylosing Spondylitis Disease Activity Score (BASDAI) and ASAS remission/partial remission criteria. ASDAS versions were also not influenced by peripheral arthritis and correlated well with other outcome measurements and acute-phase reactants. The ASDAS versions performed better than patient-reported measures or acute-phase reactants discriminating high and low disease activity status. Conclusion: Both ASDAS versions, consisting of both patient-reported data and acute-phase reactants, performed well in discriminating low and high disease activity. Further longitudinal data may better estimate the usefulness of ASDAS to assess disease activity subgroups and treatment response.en_US
dc.identifier.doi10.1111/j.1756-185X.2010.01537.x
dc.identifier.endpage245en_US
dc.identifier.issn1756-1841
dc.identifier.issue3en_US
dc.identifier.pmid20704621
dc.identifier.scopus2-s2.0-77955386556
dc.identifier.scopusqualityQ3
dc.identifier.startpage240en_US
dc.identifier.urihttps://doi.org/10.1111/j.1756-185X.2010.01537.x
dc.identifier.urihttps://hdl.handle.net/11468/17667
dc.identifier.volume13en_US
dc.identifier.wosWOS:000280628800020
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofInternational Journal of Rheumatic Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectAsdasen_US
dc.subjectDisease Activityen_US
dc.titleDiscrimination ability of ASDAS estimating disease activity status in patients with ankylosing spondylitisen_US
dc.titleDiscrimination ability of ASDAS estimating disease activity status in patients with ankylosing spondylitis
dc.typeArticleen_US

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