Evaluation of anterior segment parameters with Pentacam in children with poorly-controlled type 1 Diabetes Mellitus without diabetic retinopathy

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dc.authorid0000-0002-5299-9480en_US
dc.authorid0000-0001-5742-1293en_US
dc.authorid0000-0002-3591-721Xen_US
dc.contributor.authorKarahan, Mine
dc.contributor.authorDemirtaş, Atılım Armağan
dc.contributor.authorErdem, Seyfettin
dc.contributor.authorAva, Sedat
dc.contributor.authorDursun, Mehmet Emin
dc.contributor.authorBeştaş, Aslı
dc.contributor.authorHaspolat, Yusuf Kenan
dc.contributor.authorKeklikçi, Uğur
dc.date.accessioned2021-12-09T06:45:16Z
dc.date.available2021-12-09T06:45:16Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000627570600001
dc.descriptionPMID: 33556617
dc.description.abstracturpose: To determine the effect of abnormal glucose metabolism on the cornea, lens, anterior chamber volume (ACV), and anterior chamber depth (ACD) in children with poorly-controlled type 1 diabetes mellitus (DM) without diabetic retinopathy (DR). Methods: After the complete ophthalmologic examination of children with poorly-controlled (glycosylated hemoglobin [HbA1c] >7.0 %) type 1 DM without DR and age-matched healthy subjects (control group), the central corneal thickness (CCT), keratometry (K) values (Kmean front and back, and Kmax), radius (R) values (Rmin front and back), corneal volume (CV), ACD, ACV, pupil diameter, mean lens density (MLD), lens density standard deviation (LD SD), and maximum lens density (LD max) were measured using Pentacam High Resolution. Endothelial cell density was measured using a specular microscope. The results were assessed and compared between the two groups. Results: There were 60 patients (38 boys and 22 girls) in the DM group and 30 (14 boys, 16 girls) in the control group. There were considerable differences between the groups in terms of CCT, CV, ACD, MLD, LD SD and LD max, and Kmean back. Further, there was a positive correlation between HbA1c and MLD, LD SD, CV, and CCT in patients with DM. Conclusion: The results of our study demonstrate that poorly-controlled type 1 DM without DR affects the cornea, ACD, and LD based on anterior segment measurements taken with a Scheimpflug camera. CCT, CV, LD SD, and MLD values may be parameters that can be used to follow-up patients with type 1 DM.en_US
dc.identifier.citationKarahan, M., Demirtaş, A. A., Erdem, S., Ava, S., Dursun, M. E., Beştaş, A. ve diğerleri. (2021). Evaluation of anterior segment parameters with Pentacam in children with poorly-controlled type 1 Diabetes Mellitus without diabetic retinopathy. Photodiagnosis and Photodynamic Therapy, 33, 1-4.en_US
dc.identifier.doi10.1016/j.pdpdt.2021.102206
dc.identifier.endpage4en_US
dc.identifier.issn1572-1000
dc.identifier.pmid33556617
dc.identifier.scopus2-s2.0-85100864306
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/11468/8382
dc.identifier.volume33en_US
dc.identifier.wosWOS:000627570600001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKarahan, Mine
dc.institutionauthorErdem, Seyfettin
dc.institutionauthorAva, Sedat
dc.institutionauthorBeştaş, Aslı
dc.institutionauthorHaspolat, Yusuf Kenan
dc.institutionauthorKeklikçi, Uğur
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetic keratopathyen_US
dc.subjectLens densityen_US
dc.subjectPentacamen_US
dc.subjectPoor glycemic controlen_US
dc.subjectType 1 diabetesen_US
dc.titleEvaluation of anterior segment parameters with Pentacam in children with poorly-controlled type 1 Diabetes Mellitus without diabetic retinopathyen_US
dc.titleEvaluation of anterior segment parameters with Pentacam in children with poorly-controlled type 1 Diabetes Mellitus without diabetic retinopathy
dc.typeArticleen_US

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