Isotretinoin embryopathy. An entity that can be avoided

dc.contributor.authorCammarata-Scalisi, Francisco
dc.contributor.authorNieves, Dairelis
dc.contributor.authorAvendano, Andrea
dc.contributor.authorLacruz-Rengel, Maria A.
dc.contributor.authorAlviarez, Karelys
dc.contributor.authorDavila, Francys
dc.contributor.authorYavuz, Izzet
dc.date.accessioned2024-04-24T17:27:51Z
dc.date.available2024-04-24T17:27:51Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractIsotretinoin is the most effective drug in the treatment of severe recalcitrant nodulocystic acne. However, treatment with this drug is associated with adverse effects, the most severe being teratogenesis. It has been estimated that 40% of pregnancies exposed to isotretinoin present spontaneous abortion and 35% develop embryopathy. We present the case of a newborn with a history of prenatal exposure to isotretinoin, a clinical entity that can be avoided, with severe congenital defects in the central nervous system and important facial dysmorphisms, with unfavorable clinical course.en_US
dc.identifier.doi10.5546/aap.2018.e303
dc.identifier.endpageE307en_US
dc.identifier.issn0325-0075
dc.identifier.issn1668-3501
dc.identifier.issue2en_US
dc.identifier.pmid29557621
dc.identifier.scopus2-s2.0-85045507884
dc.identifier.scopusqualityQ3
dc.identifier.startpageE303en_US
dc.identifier.urihttps://doi.org/10.5546/aap.2018.e303
dc.identifier.urihttps://hdl.handle.net/11468/20228
dc.identifier.volume116en_US
dc.identifier.wosWOS:000428743800030
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoesen_US
dc.publisherSoc Argentina Pediatriaen_US
dc.relation.ispartofArchivos Argentinos De Pediatria
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIsotretinoinen_US
dc.subjectTeratogenesisen_US
dc.subjectEmbryopathyen_US
dc.titleIsotretinoin embryopathy. An entity that can be avoideden_US
dc.titleIsotretinoin embryopathy. An entity that can be avoided
dc.typeArticleen_US

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