Neutrophil to Lymphocyte Ratio Predicts Left Ventricular Remodeling in Patients with ST Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention

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dc.contributor.authorBorekci, Abdurrezzak
dc.contributor.authorGur, Mustafa
dc.contributor.authorTurkoglu, Caner
dc.contributor.authorBaykan, Ahmet Oytun
dc.contributor.authorSeker, Taner
dc.contributor.authorSahin, Durmus Yildiray
dc.contributor.authorHarbalioglu, Hazar
dc.date.accessioned2024-04-24T17:24:11Z
dc.date.available2024-04-24T17:24:11Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground and Objectives: It has been demonstrated that the neutrophil/lymphocyte ratio (NLR) might be a useful marker to predict cardiovascular risk and events. We aimed to investigate the role of the NLR to predict ventricular remodeling (VR) in patients with anterior ST-elevation myocardial infarction (STEMI) who were treated with primary percutaneous coronary intervention. Subjects and Methods: We prospectively included 274 consecutive anterior STEMI patients. Echocardiography was performed during admission and at six months after myocardial infarction. VR was defined as at least 200/0 increase from baseline in left ventricular end diastolic volume. Patients were divided into two groups according to their VR status: VR (n=67) and non-VR (n=207). Total and differential leukocyte count, N -terminal pro -brain natriuretic peptide (NT-proBNP) and other biochemical markers were measured at admission and 24 hours later. Results: Compared with the non-VR group, peak creatine kinase MB (CK-MB), NT-proBNP (24 h), neutrophil/lymphocyte ratio, presence of diabetes, no-reflow frequency and wall motion score index were significantly higher in patients with VR (p<0.05 for all). On multivariate logistic regression analysis, NLR (beta=2.000, 950/o confidence interval=1.577-2.537, p<0.001) as well as peak CK-MB, NT-proBNP (24 h), WMSI and diabetes incidence were associated with VR. The cutoff value of the neutrophil/lymphocyte ratio obtained by receiver operator characteristic curve analysis was 4.25 for the prediction of VR (sensitivity: 79%, specificity: 74%). Conclusion: In patients with anterior STEMI, initial NLR and NT-proBNP measured 24 hours after admission may be useful for predicting adverse cardiovascular events including left VR.en_US
dc.identifier.doi10.4070/kcj.2016.46.1.15
dc.identifier.endpage22en_US
dc.identifier.issn1738-5520
dc.identifier.issn1738-5555
dc.identifier.issue1en_US
dc.identifier.pmid26798381en_US
dc.identifier.scopus2-s2.0-84955267416en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage15en_US
dc.identifier.urihttps://doi.org/10.4070/kcj.2016.46.1.15
dc.identifier.urihttps://hdl.handle.net/11468/19503
dc.identifier.volume46en_US
dc.identifier.wosWOS:000368568400003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKorean Soc Cardiologyen_US
dc.relation.ispartofKorean Circulation Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectRemodelingen_US
dc.subjectNeutrophilsen_US
dc.subjectLymphocytesen_US
dc.subjectBnpen_US
dc.subjectNo-Reflowen_US
dc.titleNeutrophil to Lymphocyte Ratio Predicts Left Ventricular Remodeling in Patients with ST Elevation Myocardial Infarction after Primary Percutaneous Coronary Interventionen_US
dc.typeArticleen_US

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