Increased Epicardial Fat Thickness Is Associated with Cardiac Functional Changes in Healthy Women

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dc.contributor.authorKilicaslan, Baris
dc.contributor.authorOzdogan, Oner
dc.contributor.authorAydin, Mehmet
dc.contributor.authorDursun, Huseyin
dc.contributor.authorSusam, Ibrahim
dc.contributor.authorErtas, Faruk
dc.date.accessioned2024-04-24T17:18:13Z
dc.date.available2024-04-24T17:18:13Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractEpicardial fat tissue is a visceral fat depot with anatomical and functional contiguity to the myocardium and coronary arteries. The objective of this study was to evaluate the association between epicardial fat thickness (EFT) and cardiac changes in healthy female subjects. The study population consisted of ninety-six consecutive healthy female (mean age 31.1 +/- 6.7 years) who underwent transthoracic echocardiography. EFT was measured by echocardiography. Subjects were divided into two groups according to the EFT; EFT < 6 mm and EFT >= 6 mm. The cardiac structural changes, increased left atrial volume indices (LAVI) (41.2 +/- 9.9 vs. 52.6 +/- 12.5, p = 0.001) and left ventricular mass indices (LVMI) (129.6 +/- 32.1 vs. 155.6 +/- 31.6 p < 0.05), were observed in patients with increased EFT. Myocardial tei index (MTI), which was used to evaluate both systolic and diastolic functions, was higher with increased EFT (0.44 +/- 0.07 vs. 0.48 +/- 0.08, p = 0.02). The correlation analysis revealed significant correlation between EFT and each of LAVI (r = 0.312, p = 0.002), LVMI (r = 0.301, p = 0.003), body mass index (BMI) (r = 0.8, p < 0.001), and MTI (r = 0.27, p = 0.005). Multivariate regression analysis demonstrated that EFT was associated with BMI (t = 5.28, p = 0.001), MTI (r = 2.39, p = 0.019), LVMI (r = 2.16, p = 0.01), and LAVI (r = 3.21, p = 0.002). In conclusion, EFT is an important predictor of cardiac alterations in women who are prone to obesity.en_US
dc.identifier.doi10.1620/tjem.228.119
dc.identifier.endpage124en_US
dc.identifier.issn0040-8727
dc.identifier.issn1349-3329
dc.identifier.issue2en_US
dc.identifier.pmid22976597
dc.identifier.scopus2-s2.0-84867847923
dc.identifier.scopusqualityQ1
dc.identifier.startpage119en_US
dc.identifier.urihttps://doi.org/10.1620/tjem.228.119
dc.identifier.urihttps://hdl.handle.net/11468/18672
dc.identifier.volume228en_US
dc.identifier.wosWOS:000310095500005
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTohoku Univ Medical Pressen_US
dc.relation.ispartofTohoku Journal of Experimental Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpicardial Fat Tissueen_US
dc.subjectLeft Atrial Volume Indexen_US
dc.subjectLeft Ventricular Mass Indexen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectMyocardial Tei Indexen_US
dc.titleIncreased Epicardial Fat Thickness Is Associated with Cardiac Functional Changes in Healthy Womenen_US
dc.titleIncreased Epicardial Fat Thickness Is Associated with Cardiac Functional Changes in Healthy Women
dc.typeArticleen_US

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