Biventricular myocardial performance is impaired in proportion to severity of obstructive sleep apnea

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dc.contributor.authorAkyol, Selahattin
dc.contributor.authorÇörtük, Mustafa
dc.contributor.authorBaykan, Ahmet Oytun
dc.contributor.authorKiraz, Kemal
dc.contributor.authorBörekçi, Abdürrezzak
dc.contributor.authorŞeker, Taner
dc.contributor.authorGür, Mustafa
dc.contributor.authorÇaylı, Murat
dc.date.accessioned2024-04-24T17:56:40Z
dc.date.available2024-04-24T17:56:40Z
dc.date.issued2016
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObstructive sleep apnea (OSA) is an independent risk factor for cardiovascular morbidity and death. Little information is available regarding the relationship between the severity of OSA and myocardial performance in OSA patients who have normal ejection fractions. We prospectively investigated this relationship, using the tissue-Doppler myocardial performance index (TD-MPI). We conducted overnight, full-laboratory polysomnographic examinations of 116 patients, and calculated the left and right ventricular TD-MPIs. Patients were classified into 3 groups in accordance with their apnea-hypopnea index (AHI) levels: AHImild(?5 to <15), AHImoderate (?15 to <30), and AHIsevere (?30). Left and right ventricular TD-MPI values were higher in the AHIsevere group than in the AHImild and AHImoderate groups (all P <0.05). In addition, right ventricular TD-MPI values in the AHImoderate group were higher than those in the AHImild group (P <0.05). Right ventricular TD-MPI was significantly associated with AHI (?=0.468, P <0.001), left ventricular TD-MPI, and right ventricular early-to-late filling velocities (E/A ratio) in multiple linear regression analysis. On the other hand, left ventricular TD-MPI was significantly associated with right ventricular TD-MPI and left ventricular E/A ratio (both P <0.05). Our results show that OSA severity, determined by means of AHI, is independently associated with impaired right and left ventricular function as indicated by TD-MPI in patients who have OSA and normal ejection fractions.en_US
dc.identifier.citationAkyol, S., Çörtük, M., Baykan, A. O., Kiraz, K., Börekçi, A., Şeker, T. ve diğerleri. (2016). Biventricular myocardial performance is impaired in proportion to severity of obstructive sleep apnea. Texas Heart Institute Journal, 43(2), 119-125.
dc.identifier.doi10.14503/THIJ-14-4868
dc.identifier.endpage125en_US
dc.identifier.issn0730-2347
dc.identifier.issue2en_US
dc.identifier.pmid27127425
dc.identifier.scopus2-s2.0-84962656591
dc.identifier.scopusqualityQ4
dc.identifier.startpage119en_US
dc.identifier.urihttps://doi.org/10.14503/THIJ-14-4868
dc.identifier.urihttps://hdl.handle.net/11468/23616
dc.identifier.volume43en_US
dc.identifier.wosWoSIDEksik
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTexas Heart Instituteen_US
dc.relation.ispartofTexas Heart Institute Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiovascular Diseases/Etiologyen_US
dc.subjectEchocardiography, Doppleren_US
dc.subjectHeartfunction tests/methodsen_US
dc.subjectPredictive value of testsen_US
dc.subjectProspective studiesen_US
dc.subjectRisk factorsen_US
dc.subjectSleep Apnea,Obstructive/ Classification/Complications/ Physiopathologyen_US
dc.subjectVentricular Dysfunction, Left/Diagnosis/ Etiology/Physiologyen_US
dc.subjectVentricular Dysfunction, Right/Diagnosis/ Etiology/Physiologyen_US
dc.titleBiventricular myocardial performance is impaired in proportion to severity of obstructive sleep apneaen_US
dc.titleBiventricular myocardial performance is impaired in proportion to severity of obstructive sleep apnea
dc.typeArticleen_US

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