The impact of COVID-19 on familial Mediterranean fever: a nationwide study

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dc.authorid0000-0002-4124-1586en_US
dc.contributor.authorGünendi, Zafer
dc.contributor.authorYurdakul, Fatma Gül
dc.contributor.authorBodur, Hatice
dc.contributor.authorCengiz, Ahmet Kıvanç
dc.contributor.authorUçar, Ülkü Gürbüz
dc.contributor.authorÇay, Hasan Fatih
dc.contributor.authorŞen, Nesrin
dc.contributor.authorKeskin, Yaşar
dc.contributor.authorGürer, Gülcan
dc.contributor.authorMelikoǧlu, Meltem Alkan
dc.contributor.authorAltıntaş, Duygu
dc.contributor.authorDeveci, Hülya Mutlu
dc.contributor.authorBaykul, Merve
dc.contributor.authorNas, Kemal
dc.contributor.authorÇevik, Remzi
dc.contributor.authorKarahan, Ali Yavuz
dc.contributor.authorToprak, Murat M.
dc.contributor.authorKetenci, Sertaç
dc.contributor.authorNayimoğlu, Mehmet
dc.contributor.authorSezer, İlhan
dc.contributor.authorDemir, Ali Nail
dc.contributor.authorEcesoy, Hilal
dc.contributor.authorDuruöz, Tuncay
dc.contributor.authorVolkan Yurdakul, Ozan
dc.contributor.authorSarıfakıoğlu, Ayşe Banu
dc.contributor.authorAtaman, Şebnem
dc.date.accessioned2022-05-06T11:28:59Z
dc.date.available2022-05-06T11:28:59Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalıen_US
dc.descriptionPMID: 34032894
dc.descriptionWOS:000654089100002
dc.description.abstractThe study aimed to evaluate the impact of the coronavirus disease 2019 (COVID-19) in patients with familial Mediterranean fever (FMF) and to assess the relationships between FMF characteristics and severe COVID-19 outcomes such as hospitalization. The study was planned within a national network of 21 different centers. Demographics, FMF-related clinical and genetic characteristics, and COVID-19 outcomes were obtained. A total of 822 patients with FMF (mean age of 36 years) were included in the study. Fifty-nine of them (7%) had a COVID-19 diagnosis confirmed by real-time PCR test or chest CT findings. Most FMF patients with COVID-19 (58) had mild and moderate disease activity. All patients were on colchicine treatment. However, 8 of them (13.6%) were not compliant with colchicine use and 9 of them (15.3%) were colchicine resistant. Twelve FMF patients with COVID-19 were hospitalized. There were 4 patients requiring oxygen support. COVID-19 related complications were observed in 2 patients (1 thromboembolism, 1 acute respiratory distress syndrome). Hospitalized COVID-19 patients with FMF were older than non-hospitalized patients (median ages: 51 and 31 years, respectively; p: 0.002). Other FMF-related characteristics were similar between the groups. FMF-related characteristics were not found to be associated with poor outcomes in COVID-19. Thus, FMF may not be a risk factor for poor COVID-19 outcomes.en_US
dc.identifier.citationGünendi, Z., Yurdakul, F. G., Bodur, H., Cengiz, A. K., Uçar, Ü. G., Çay, H. F. ve diğerleri (2021). The impact of COVID-19 on familial Mediterranean fever: a nationwide study. Rheumatology International, 41(8), 1447-1455.en_US
dc.identifier.doi10.1007/s00296-021-04892-6
dc.identifier.endpage1455en_US
dc.identifier.issn0172-8172
dc.identifier.issue8en_US
dc.identifier.pmid34032894
dc.identifier.scopus2-s2.0-85106463983
dc.identifier.scopusqualityQ1
dc.identifier.startpage1447en_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s00296-021-04892-6
dc.identifier.urihttps://hdl.handle.net/11468/9804
dc.identifier.volume41en_US
dc.identifier.wosWOS:000654089100002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇevik, Remzi
dc.language.isotren_US
dc.publisherSpringer Science and Business Media Deutschland GmbHen_US
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColchicineen_US
dc.subjectCOVID-19en_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectHospitalizationen_US
dc.subjectPoor outcomesen_US
dc.subjectRheumatic diseasesen_US
dc.titleThe impact of COVID-19 on familial Mediterranean fever: a nationwide studyen_US
dc.titleThe impact of COVID-19 on familial Mediterranean fever: a nationwide study
dc.typeArticleen_US

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