A comparison of propofol-midazolam and midazolam alone for sedation in endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective cohort study

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dc.contributor.authorOztas, Selahattin
dc.contributor.authorAkturk, Ulku Aka
dc.contributor.authorAlpay, Levent A.
dc.contributor.authorMeydan, Burhan
dc.contributor.authorOgun, Hamza
dc.contributor.authorTaylan, Mahsuk
dc.contributor.authorYalcinsoy, Murat
dc.date.accessioned2024-04-24T17:11:26Z
dc.date.available2024-04-24T17:11:26Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectivesEndobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a new, minimally invasive, bronchoscopic technique used in the evaluation of inthrathoracic lymph nodes.Use of sedation drugs before the procedure differs among centres. There is no standardization about sedation before EBUS-TBNA.We used a policy decision to shift from use of propofol with midazolam vs midazolam alone in a large tertiary hospital to evaluate the diagnostic yield and safety of EBUS-TBNA procedure. MethodsFiles of all the patients who were performed EBUS-TBNA between the dates of September 2010 and May 2014 were surveyed. All the EBUS-TBNA cases were performed under sedation of propofol and midazolam with an accompanying anesthesiologist in the beginning, however, sedation is applied with midazolam without an accompanying anesthesiologist after April 2013 due to changes in sedation policy. The diagnostic yield and complication rates were compared by chi-squared analysis between two groups. ResultsThe files of 340 EBUS-TBNA performed patients were evaluated. Of the patients 274 eligible patients were analysed. 152 patients who fulfilled the inclusion criteria were analysed in propofol-midazolam (P) sedated group and 122 patients were analysed in midazolam (M) group. There is no statistically significant difference between two different sedated groups in terms of age and gender. Diagnostic value was detected as 77.6% in P group and 85.7% in M group and the difference was not statistically significant. No difference between complication rates of both groups was observed. ConclusionBoth sedation-types for performing EBUS-TBNA showed similar diagnostic value and complication rates in our study. Propofol with midazolam application requires with an accompanying anaesthesiologist, therefore, it increases cost. EBUS-TBNA procedures had been performed in safe with no decrease in diagnostic yield under moderate sedation.en_US
dc.identifier.doi10.1111/crj.12442
dc.identifier.endpage941en_US
dc.identifier.issn1752-6981
dc.identifier.issn1752-699X
dc.identifier.issue6en_US
dc.identifier.pmid26720178
dc.identifier.scopus2-s2.0-84959431862
dc.identifier.scopusqualityQ3
dc.identifier.startpage935en_US
dc.identifier.urihttps://doi.org/10.1111/crj.12442
dc.identifier.urihttps://hdl.handle.net/11468/17518
dc.identifier.volume11en_US
dc.identifier.wosWOS:000415356900038
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Respiratory Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEbus-Tbnaen_US
dc.subjectSedationen_US
dc.subjectPropofolen_US
dc.subjectMidazolamen_US
dc.titleA comparison of propofol-midazolam and midazolam alone for sedation in endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective cohort studyen_US
dc.titleA comparison of propofol-midazolam and midazolam alone for sedation in endobronchial ultrasound-guided transbronchial needle aspiration: a retrospective cohort study
dc.typeArticleen_US

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